The chemistry and some biological effects of the cytochalasins [PDF]
Biochemical Journal, 1972 W B Turner, S B Carter
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Recovery of aging-related size increase of skin epithelial cells: in vivo mouse and in vitro human study. [PDF]
PLoS ONE, 2015 The size increase of skin epithelial cells during aging is well-known. Here we demonstrate that treatment of aging cells with cytochalasin B substantially decreases cell size.
Igor Sokolov +6 more
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Cytoskeletal Remodeling Mimics Endothelial Response to Microgravity
Frontiers in Cell and Developmental Biology, 2021 Mechanical cues contribute to the maintenance of a healthy endothelium, which is essential for vascular integrity. Indeed endothelial cells are mechanosensors that integrate the forces in the form of biochemical signals.
Laura Locatelli +2 more
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In vitro markers for virulence in Yersinia ruckeri [PDF]
, 2010 In this study, different traits that have been associated with bacterial virulence were studied in Yersinia ruckeri. Two isolates that had been shown to cause disease and mortality in experimentally infected rainbow trout were compared with five ...
Chiers, Koen +5 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
An enantioselective, modular, and general route to the cytochalasins: Synthesis of L-696,474 and cytochalasin B [PDF]
Proceedings of the National Academy of Sciences, 2004 The cytochalasins are structurally complex natural products with a broad range of apparently unrelated effects in different biological systems. Different members of the family have variously demonstrated inhibitory activity toward the formation of actin filaments, toward the functioning of HIV protease, and toward the process of angiogenesis.
Andrew G. Myers, Andrew M. Haidle
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Molecular docking study of cytochalasin H and Fascin interactions as prospective targets for gastric cancer [PDF]
Jorjani Biomedicine Journal, 2023 Background: Gastric cancer is the fifth most common neoplasm and the fourth leading cause of mortality worldwide. Incidence rates vary widely and depend on risk factors, epidemiological factors, and carcinogenesis patterns.
Samaneh Heidarzadeh +1 more
doaj
Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells. [PDF]
, 2018 Image mean square displacement analysis (iMSD) is a method allowing the mapping of diffusion dynamics of molecules in living cells. However, it can also be used to obtain quantitative information on the diffusion processes of fluorescently labelled ...
Davey, Rhonda J +3 more
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Translational Oncology, 2015 An effective and inexpensive protocol for producing cytochalasins A and B is being disclosed to propose a viable method by which to examine the in vivo antineoplastic activity of these congeners in preclinical tumor-bearing mammalian models. In addition,
Matthew Trendowski +4 more
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Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum. [PDF]
, 2019 We previously showed that Entamoeba histolytica kills human cells through a mechanism that we termed trogocytosis ("trogo-" means "nibble"), due to its resemblance to trogocytosis in other organisms. In microbial eukaryotes like E.
Miller, Hannah W +2 more
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