Results 51 to 60 of about 45,867 (238)

Major Constituents of the Predominant Endophytic Fungi from the Nigerian Plants and

Natural Product Communications, 2008
In a chemical screening of fungal strains endophytic to Nigerian plants, Diaporthe phaseolorum , the endophyte of Bryophyllum pinnatum , gave cytochalasin D and (3 R ,4 R )-3,4,5-trihydroxy-1-tetralone, Neurospora discreta from Morinda lucida yielded ...
Abimbola A. Sowemimo, RuAngelie Edrada-Ebel, Rainer Ebel, Peter Proksch, Olanrewaju R. Omobuwajo, Saburi A. Adesanya   +5 more
doaj   +1 more source

Cell contractile force measured using a deformable hollow capsule

The EuroBiotech Journal, 2022
There are several possible ways to measure the contraction of cells in vitro. Here, we report measurements of the contractile properties of 3T3-L1 cells grown to confluence on 3D hollow capsules.
Ting Julia Ho Yee, Martin Donald K
doaj   +1 more source

Cell contraction induces long-ranged stress stiffening in the extracellular matrix [PDF]

, 2017
Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains largely unknown ...
Broedersz, Chase P., Guo, Ming, Han, Yu Long, Kamm, Roger, Lenz, Martin, Malandrino, Andrea, Ronceray, Pierre, Xu, Guoqiang   +7 more
core   +2 more sources

Coacervate‐Mediated Lysosome‐Targeting Antibody Delivery for Protein Degradation

Advanced Science, EarlyView.
Targeting coacervates to the lysosome in the cytoplasm is a challenge. Here, we convert a tetrapeptide into lysosome‐targeting, membrane‐translocating coacervates. The lysosome‐sorting peptide coacervates facilitate coacervate‐mediated delivery of antibody antigen complexes and a PROTAC compound to the lysosome for the targeted degradation of cancer ...
Dingdong Yuan, Yishu Bao, Zhiyi Xu, Zhong Zheng, Yongxu Han, Kai Cheng, Yuan‐Di Zhao, Jiang Xia   +7 more
wiley   +1 more source

Cytochalasins from the Ash Endophytic Fungus Nemania diffusa DSM 116299

Molecules
The secondary metabolome of Nemania diffusa, isolated as an ash endophytic fungus, was analyzed in detail. From its cultures, a previously undescribed cytochalasin 1 was isolated using preparative HPLC, together with six known congeners: 18-dehydroxy ...
Özge Demir, Katharina Schmidt, Barbara Schulz, Theresia E. B. Stradal, Frank Surup   +4 more
doaj   +1 more source

Optical measurement of osmotic water transport in cultured cells. Role of glucose transporters. [PDF]

, 1992
Methodology was developed to measure osmotic water permeability in monolayer cultured cells and applied to examine the proposed role of glucose transporters in the water pathway (1989. Proc. Natl. Acad. Sci. USA. 86:8397-8401).
Echevarria, M, Verkman, AS
core  

Fusion of isolated myoblast plasma membranes [PDF]

, 1978
Fusion of plasma membranes isolated from myoblasts grown in culture has been investigated. 1. 1. Membrane fusion was specifically dependent on Ca2+ at physiological concentrations. However, at higher concentrations of cations, fusion could be triggered
Ahkong, Batzri, Berl, Berlin, Burwen, Croce, Dahl, Dahl, Dahl, De Camilli, Douglas, Dreifuss, Fairbanks, Gratzl, Gratzl, Gratzl, Hauser, Holtzer, Kalderon, Kantor, Kent, Lawson, Lee, Maeda, Martin, Okada, Okada, Onishi, Orci, Pagano, Papahadjopoulos, Papahadjopoulos, Papahadjopoulos, Papahadjopoulos, Pauli, Peretz, Poole, Poste, Prives, Rash, Reed, Reeves, Sanger, Satir, Schimmel, Schlessinger, Schudt, Schudt, Schudt, Schudt, Shainberg, Shainberg, Van den Bosch, Van den Bosch, Van den Bosch, Vos, Weidekamm, Weidekamm, Yanofsky, Zakai   +59 more
core   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig

Journal of Physiological Sciences
Actin linked regulatory mechanisms are known to contribute contraction/relaxation in smooth muscle. In order to clarify whether modulation of polymerization/depolymerization of actin filaments affects relaxation process, we examined the effects of ...
Satoko Mihashi, Masaru Watanabe
doaj   +1 more source

Modulation of TMEM16A-Channel Activity as Ca2+ Activated Cl− Conductance via the Interaction With Actin Cytoskeleton in Murine Portal Vein

Journal of Pharmacological Sciences, 2014
.: TMEM16A is a major component of Ca2+-activated Cl− channel (CaCC) conductance in murine portal vein smooth muscle cells (mPVSMCs). Here, the regulation of CaCC activity by the actin cytoskeleton was examined in mPVSMCs.
Junya Ohshiro, Hisao Yamamura, Yoshiaki Suzuki, Yuji Imaizumi   +3 more
doaj   +1 more source