Results 221 to 230 of about 18,833 (262)

Cytochalasin D‐induced triploidy in the mouse

Journal of Experimental Zoology, 1989
AbstractPrevious attempts to obtain digynic triploid mouse development in vivo have either been entirely or only marginally successful, generally with the production of heteroploid rather than triploid conceptuses. We report that when a single intraperitoneal injection of 15 üg of cytochalasin D is given to recently mated female mice during a ...
S. Speirs, M. H. Kaufman
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On the molecular basis of action of cytochalasin B

Journal of Supramolecular Structure, 1974
AbstractTritium‐labeled cytochalasin B binds rapidly and reversibly to mammalian cells, and a class of high‐affinity sites (Kn ≅ 10−7 M) and a class of low‐affinity sites (KD ⩾ 10−5 M) are detected. In red blood cells, the high‐affinity binding sites (about 3 × 105 per cell) are associated with the plasma membrane, and at least 80% of these appear to ...
Shin Lin, James A. Spudich
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Cytochalasin-u and Cytochalasin-v, 2 New Cytochalasins, From Phoma-exigua Var Heteromorpha

1992
Two additional cytochalasins were isolated from liquid culture filtrates of Phoma exiqua var. heteromorpha together with some already known cytochalasins. The two new metabolites, named cytochalasin U and V, represent the first natural occurrence of a 25,26-dioxa[16] and 25-oxa[15]cytochalasan, respectively, both bearing a formyl group on the ...
EVIDENTE, ANTONIO, LANZETTA, ROSA, R. CAPASSO, M. VURRO, A. BOTTALICO   +4 more
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The reaction of cytochalasin a with sulfhydryl groups

Biochemical and Biophysical Research Communications, 1976
Abstract The reaction of cytochalasin A with sulfhydryl groups was examined. Cysteine and glutathione reacted readily with cytochalasin A at pH 7.0, 20°C, following second-order kinetics with rate constants of 7,600 M −1 sec −1 and 870 × 10 3 M −1 sec −1 . No reaction of cytochalasin B could be demonstrated under the same conditions. The reaction
openaire   +3 more sources

In vitro growth inhibitory effects of cytochalasins and derivatives in cancer cells.

Planta Medica, 2011
The in vitro anticancer activity of eight natural cytochalasins and three hemisynthetic derivatives of cytochalasin B on six cancer cell lines was evaluated.
Gwendoline Van Goietsenoven, V. Mathieu, A. Andolfi, A. Cimmino, F. Lefranc, R. Kiss, A. Evidente   +6 more
semanticscholar   +1 more source

Structure-activity correlations of cytochalasins. Novel halogenated and related cytochalasin C and D derivatives

Journal of Medicinal Chemistry, 1982
AbstractDie Bromierung von Cytochalasin D (CD) (I) mit Phenyltrimethylammoniumtribromid liefert das 6,12‐Dibromo‐CD (II).
Michael Flashner, Stuart W. Tanenbaum, Carl A. Miller, Bhalchandra H. Patwardhan   +3 more
openaire   +4 more sources

Structures of cytochalasins C and D

Journal of the Chemical Society C: Organic, 1969
The structures of cytochalasins C and D, metabolites of Metarrhizium anisopliae, have been determined.
D. C. Aldridge, W. B. Turner
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Isolation of cytochalasins A and B fromAscochyta lathyri

Mycotoxin Research, 1992
The possible presence of toxic metabolites in the culture extracts of 24Ascochyta strains, grown on autoclaved wheat, was ascertained by the use of the biological assay on brine shrimps (Artemia salina). Only in the culture extract ofA lathyri, that showed a very high toxicity, the presence of cytochalasins A and B was revealed by tlc,(1)H nmr and fab ...
Vurro M, Zonno MC, Evidente A, Capasso R, Bottaiico A   +4 more
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Binding of cytochalasin B to platelets

Journal of Cellular Biochemistry, 1989
AbstractThe binding of cytochalasin B (CB) to human platelets and to isolated platelet cytosol and membranes has been analyzed with [3H]CB. High‐ and low affinity classes of saturable binding sites were associated with intact platelets. Binding at very low concentrations of CB (i.e., high‐affinity binding) was partially prevented by 100 mM D‐galatose ...
openaire   +3 more sources

New Cytochalasins from the Marine-Derived Fungus Xylaria sp. SCSIO 156

, 2011
Two new cytochalasins, 18-deoxycytochalasin Q (1) and 21-O-deacetylcytochalasin Q (2), together with four known analogues, cytochalasin Q (3), 19,20-epoxycytochalasin Q (4), 21-O-deacetyl-19,20-epoxycytochalasin Q (5), and cytochalasin D (6), were ...
Ziming Chen, Hongbo Huang, Yuchan Chen, Zhongwen Wang, Junying Ma, Bo Wang, Weimin Zhang, Changsheng Zhang, J. Ju   +8 more
semanticscholar   +1 more source