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Cytochalasin-u and Cytochalasin-v, 2 New Cytochalasins, From Phoma-exigua Var Heteromorpha
1992Two additional cytochalasins were isolated from liquid culture filtrates of Phoma exiqua var. heteromorpha together with some already known cytochalasins. The two new metabolites, named cytochalasin U and V, represent the first natural occurrence of a 25,26-dioxa[16] and 25-oxa[15]cytochalasan, respectively, both bearing a formyl group on the ...
EVIDENTE, ANTONIO +4 more
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Cytochalasin B inhibits thyroid secretion
Biochemical and Biophysical Research Communications, 1971The addition in vitro of cytochalasin B at concentrations of 0.5–3.0 μg/ml to prelabeled mouse thyroid glands interferes with release of iodine derived from thyroglobulin and blocks colloid endocytosis. It is suggested that cytoplasmic microfilaments are involved in the secretory process.
J A, Williams, J, Wolff
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Archives of Biochemistry and Biophysics, 1988
The effects on actin self-assembly of 9 common cytochalasins and 9 synthetic analogs have been assayed using fluorescence photobleaching recovery (FPR). The specific assembly activities of cytochalasins determined by this assay are (i) reduction of the fraction of actin molecules incorporated into filaments; (ii) increase of the steady-state diffusion ...
E A, Walling, G A, Krafft, B R, Ware
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The effects on actin self-assembly of 9 common cytochalasins and 9 synthetic analogs have been assayed using fluorescence photobleaching recovery (FPR). The specific assembly activities of cytochalasins determined by this assay are (i) reduction of the fraction of actin molecules incorporated into filaments; (ii) increase of the steady-state diffusion ...
E A, Walling, G A, Krafft, B R, Ware
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Cytochalasin B induces cellular DNA fragmentation
The FASEB Journal, 1990Cellular DNA fragmentation can be induced in many biological instances without plasma membrane damage. The fungal metabolite, cytochalasin B, is capable of modifying numerous cellular functions related to DNA synthesis. In this work it is demonstrated that cytochalasin B is capable of inducing DNA fragmentation in a number of cells
M A, Kolber +2 more
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Cytochalasin sensitive structures and lymphocyte activation
Experimental Cell Research, 1976Abstract In purified human peripheral blood lymphocytes, low (0.01–10 μM) concentrations of cytochalasins A B, E and D (CA, CB, CD, CE) produced marked augmentation of transport and metabolic responses to phytohemagglutinin (PHA) and concanavalin A (ConA) including effects on DNA synthesis, cAMP accumulation, phosphatidylinositol turnover and sodium ...
W C, Greene, C M, Parker, C W, Parker
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Cytochalasin D fromHypocrella Bambusae
Journal of Asian Natural Products Research, 2001Cytochalasin D which shows marked cytotoxic effects on multi-tumor cells was newly isolated at high content(5.28 mg/g, dry weight) from Fungus Hypocrella bambusae(B.et Br.) Sacc. Its structure was elucidated by spectroscopic methods. Two-dimensional NMR techniques were applied to make complete assignment for the 1H- and 13C-NMR chemical shifts of this ...
H, Xu +4 more
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Cytochalasins from Phoma exigua var. Heteromorpha
Phytochemistry, 1991Abstract Three further cytochalasins from Phoma exigua var. heteromorpha , grown on wheat, were isolated and characterized by spectroscopic methods and by chemical correlation with cytochalasin B. They were identified as cytochalasin T, a new 24-oxa[14]cytochalasan, cytochalasin F and 7- O -acetylcytochalasin B, both isolated for the first time ...
Capasso R, Evidente A, Vurro M
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Ascochalasin, a New Cytochalasin from Ascochyta heteromorpha
Journal of Natural Products, 1988[object Object]
R. CAPASSO +5 more
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