Results 41 to 50 of about 271,428 (260)

Role of lysines in cytochrome c – cardiolipin interaction [PDF]

, 2013
Cytochrome c undergoes structural variations during the apoptotic process; such changes have been related with modifications occurring in the protein when it forms a complex with cardiolipin, one of the phospholipids constituting the mitochondrial ...
Coletta, M, Di Pierro, D, Droghetti, E, Fiorucci, L, Howes, B, Piro, MC, Polticelli, F, Santucci, R, Sinibaldi, F, Smulevich, G   +9 more
core   +1 more source

Effects of Laser Radiation on Mitochondria and Mitochondrial Proteins Subjected to Nitric Oxide

Frontiers in Medicine, 2018
The biological roles of heme and nonheme nitrosyl complexes in physiological and pathophysiological conditions as metabolic key players are considered in this study. Two main physiological functions of protein nitrosyl complexes are discussed—(1) a depot
Anatoly N. Osipov, Tatiana V. Machneva, Evgeny A. Buravlev, Evgeny A. Buravlev, Yury A. Vladimirov, Yury A. Vladimirov   +5 more
doaj   +1 more source

The Naturally Occurring A51V Variant of Human Cytochrome c Destabilizes the Native State and Enhances Peroxidase Activity.

Journal of Physical Chemistry B, 2019
The A51V variant of human cytochrome c is linked to thrombocytopenia 4 (THC4), a condition that causes decreased blood platelet counts. A 1.82 Å structure of the A51V variant shows only minor changes in tertiary structure relative to the wild type (WT ...
Haotian Lei, B. Bowler
semanticscholar   +1 more source

ABTS oxidation reaction as a model of cytochrome c-driven electron transfer [PDF]

The Ukrainian Biochemical Journal
Cytochrome c, as an electron carrier within the mitochondria, plays a crucial role in the electron transport chain. To meet the demand for rapid methods that assess the electron transport properties of cytochrome c, we used the electron donor 2,2′-azino ...
F. Gudratova, A. Aliyeva, S. Mahmudova, K. Gasimov, T. Yusifov   +4 more
doaj   +1 more source

Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle

Nature Communications, 2023
Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational modifications of cytochrome c (Cytc) are involved in ischemia-reperfusion injury by regulating mitochondrial respiration and apoptosis.
Paul T. Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A. Turner, Inmaculada Márquez, Hasini A. Kalpage, Asmita Vaishnav, Matthew P. Zurek, Philipp P. Huettemann, Katherine Kim, Tasnim Arroum, Miguel A. De la Rosa, Dipanwita Dutta Chowdhury, Icksoo Lee, Joseph S. Brunzelle, Thomas H. Sanderson, Moh H. Malek, David Meierhofer, Brian F. P. Edwards, Irene Díaz-Moreno, Maik Hüttemann   +20 more
doaj   +1 more source

Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria [PDF]

, 2018
Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective insulin treatment, but how such posttranslational modification affects mitochondrial metabolism is unclear.
Díaz Moreno, Irene, Díaz Quintana, Antonio Jesús, Elena-Real, Carlos A., García Mauriño, Sofía M., González Arzola, Katiuska, Guerra Castellano, Alejandra, Pérez Mejías, Gonzalo, Rosa Acosta, Miguel Ángel de la   +7 more
core   +1 more source

Hydrogen-rich water treatment improves fresh-cut Gastrodia elata quality by regulating reactive oxygen species metabolism and energy metabolism during low temperature storage

Frontiers in Sustainable Food Systems, 2023
The application of hydrogen-rich water (HRW) can extend the shelf life of fruits and vegetables. This study aims to investigate the effects of HRW on the quality of fresh-cut Gastrodia elata during low-temperature (4°C) storage. The results indicate that
Boyu Dong, Boyu Dong, Dequan Zhu, Dequan Zhu, Qiuping Yao, Qiuping Yao, Fangfang Da, Fangfang Da, Yulong Chen, Yulong Chen, Xiaochun Ding   +10 more
doaj   +1 more source

Lysine carbonylation is a previously unrecognized contributor to peroxidase activation of cytochrome c by chloramine-T

Chemical Science, 2019
Ion mobility-assisted tandem MS uncovers hitherto overlooked modifications that are critical for the peroxidase activity of chloramine T-modified cytochrome c.
Victor C. Yin, Safee Mian, L. Konermann
semanticscholar   +1 more source

Tamoxifen-like metallocifens target thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells [PDF]

, 2017
Tamoxifen-like metallocifens (TLMs) of the group-8 metals (Fe, Ru, and Os) show strong anti-proliferative activity on cancer cell lines resistant to apoptosis, owing to their unique redox properties. In contrast, the thioredoxin system, which is involved
Alberto Bindoli, Alessandra Folda, Anne Vessières, Gérard Jaouen, Hui Zhi Shirley Lee, Maria Pia Rigobello, Michèle Salmain, Pascal Pigeon, Siden Top, Valeria Scalcon   +9 more
core   +3 more sources

Acute Alcohol Tissue Damage: Protective Properties of Betaine

Journal of Renal and Hepatic Disorders, 2021
Teenage binge drinking is a major health issue; however, there is a paucity of data on liver injury. Herein, we investigated how acute ethanol affects juvenile hepatic cells through changes in oxidative stress, apoptosis, and liver function, as well as ...
Lucy Petagine, Hannah Everitt, Victor Preedy, Roy Sherwood, Vinood Patel   +4 more
doaj   +1 more source