Results 1 to 10 of about 373,942 (257)
Inhibitors of cytochrome c biogenesis pathways [PDF]
mBioThe unique composition of bacterial electron transport chains (ETCs), distinct from the human mitochondrial ETC, presents opportunities for selective antibacterial targeting.
Deanna L. Mendez +8 more
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Dimerization-induced conformational transitions of yeast iso-1 cytochrome c [PDF]
Magnetic Resonance LettersCytochrome c is a multifunctional protein involved in electron transport and apoptosis. However, its conformational landscape is complex and heterogeneous, which has obscured the functional understanding—particularly regarding its long-observed dimerized
Qianwen Wang +13 more
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Cytochrome c Negatively Regulates NLRP3 Inflammasomes. [PDF]
PLoS ONE, 2016 The release of cytochrome c from the inner mitochondrial membrane, where it is anchored by caridolipin, triggers the formation of the Apaf-1 apoptosome. Cardiolipin also interacts with NLRP3 recruiting NLRP3 to mitochondria and facilitating inflammasome ...
Chong-Shan Shi, John H Kehrl
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Interspecies Variation in the Functional Consequences of Mutation of Cytochrome c. [PDF]
PLoS ONE, 2015 The naturally occurring human cytochrome c variant (G41S) is associated with a mild autosomal dominant thrombocytopenia (Thrombocytopenia Cargeeg) caused by dysregulation of platelet production.
Tracy M Josephs +4 more
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New insight into the mechanism of mitochondrial cytochrome c function. [PDF]
PLoS ONE, 2017 We investigate functional role of the P76GTKMIFA83 fragment of the primary structure of cytochrome c. Based on the data obtained by the analysis of informational structure (ANIS), we propose a model of functioning of cytochrome c. According to this model,
Rita V Chertkova +9 more
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Lysine-PEGylated Cytochrome C with Enhanced Shelf-Life Stability
Biosensors, 2022 Cytochrome c (Cyt-c), a small mitochondrial electron transport heme protein, has been employed in bioelectrochemical and therapeutic applications. However, its potential as both a biosensor and anticancer drug is significantly impaired due to poor long ...
João H. P. M. Santos +6 more
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Multiple Mechanisms Regulate Eukaryotic Cytochrome C Oxidase
Cells, 2021 Cytochrome c oxidase (COX), the rate-limiting enzyme of mitochondrial respiration, is regulated by various mechanisms. Its regulation by ATP (adenosine triphosphate) appears of particular importance, since it evolved early during evolution and is still ...
Rabia Ramzan +2 more
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In-silico assessment of protein-protein electron transfer. a case study: cytochrome c peroxidase--cytochrome c. [PDF]
PLoS Computational Biology, 2013 The fast development of software and hardware is notably helping in closing the gap between macroscopic and microscopic data. Using a novel theoretical strategy combining molecular dynamics simulations, conformational clustering, ab-initio quantum ...
Frank H Wallrapp +2 more
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Mitochondrial Encephalopathy and Cytochrome C
Pediatric Neurology Briefs, 1997 Benefits from treatment of mitochondrial encephalomyopathy (MEM) with cytochrome C (6.25 mg) and vitamins Bl (25 mg) and B2 (12.5 mg), in daily injections, are reported from Osaka University Medical School and other centers in Japan.
J Gordon Millichap
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Electron transfer interactome of cytochrome C.
PLoS Computational Biology, 2012 Lying at the heart of many vital cellular processes such as photosynthesis and respiration, biological electron transfer (ET) is mediated by transient interactions among proteins that recognize multiple binding partners.
Alexander N Volkov, Nico A J van Nuland
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