Results 31 to 40 of about 40,950,057 (342)

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance This paper describes the finding that mitochondria synthesize and release melatonin and have their selective G protein-coupled receptor (GPCR) in the outer membrane.
Y. Suofu   +35 more
semanticscholar   +1 more source

The aggregation of cytochrome C may be linked to its flexibility during refolding [PDF]

open access: yes, 2016
Large-scale expression of biopharmaceutical proteins in cellular hosts results in production of large insoluble mass aggregates. In order to generate functional product, these aggregates require further processing through refolding with denaturant, a ...
James I. Austerberry   +5 more
core   +2 more sources

ABTS oxidation reaction as a model of cytochrome c-driven electron transfer [PDF]

open access: yesThe Ukrainian Biochemical Journal
Cytochrome c, as an electron carrier within the mitochondria, plays a crucial role in the electron transport chain. To meet the demand for rapid methods that assess the electron transport properties of cytochrome c, we used the electron donor 2,2′-azino ...
F. Gudratova   +4 more
doaj   +1 more source

The anti-apoptotic Bcl-x(L) protein, a new piece in the puzzle of cytochrome c interactome. [PDF]

open access: yesPLoS ONE, 2011
A structural model of the adduct between human cytochrome c and the human anti-apoptotic protein Bcl-x(L), which defines the protein-protein interaction surface, was obtained from solution NMR chemical shift perturbation data.
Ivano Bertini   +4 more
doaj   +1 more source

Accelerated Evolution of Cytochrome c in Higher Primates, and Regulation of the Reaction between Cytochrome c and Cytochrome Oxidase by Phosphorylation

open access: yesCells, 2022
Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand   +10 more
doaj   +1 more source

Mitochondrial Cytochrome c Oxidase Biogenesis: Recent Developments

open access: yesSeminars in Cell and Developmental Biology, 2017
Mitochondrial cytochrome c oxidase (COX) is the primary site of cellular oxygen consumption and is essential for aerobic energy generation in the form of ATP.
Alba Timón-Gómez   +5 more
semanticscholar   +1 more source

Biogenesis of cytochrome c1 [PDF]

open access: yes, 1989
The biogenesis of cytochrome c1 involves a number of steps including: synthesis as a precursor with a bipartite signal sequence, transfer across the outer and inner mitochondrial membranes, removal of the first part of the presequence in the matrix ...
Stuart, Rosemary A.   +2 more
core   +1 more source

Rcf1 Modulates Cytochrome c Oxidase Activity Especially Under Energy-Demanding Conditions

open access: yesFrontiers in Physiology, 2020
The mitochondrial respiratory chain is assembled into supercomplexes. Previously, two respiratory supercomplex-associated proteins, Rcf1 and Rcf2, were identified in Saccharomyces cerevisiae, which were initially suggested to mediate supercomplex ...
Hannah Dawitz   +5 more
doaj   +1 more source

Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1

open access: yesNature Structural & Molecular Biology, 2018
Cytochrome c oxidase (complex IV, CIV) is known in mammals to exist independently or in association with other respiratory proteins to form supercomplexes (SCs).
A. M. Hartley   +7 more
semanticscholar   +1 more source

Cytochrome C Oxidase Deficiency and Respiratory Distress

open access: yesPediatric Neurology Briefs, 1989
A newborn male presenting with severe respiratory insufficiency, generalized muscle weakness, and lactic acidemia is reported from the Department of Pediatrics, Nagasaki University School of Medicine, Japan.
J Gordon Millichap
doaj   +1 more source

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