Results 21 to 30 of about 40,950,057 (342)
Biosensors, 2023 Cytochrome c (Cytc) is a key redox protein for energy metabolism and apoptosis in cells. The activation of Cytc is composed of several steps, including its transfer to the mitochondrial membrane, binding to cytochrome c heme lyase (CCHL) and covalent ...
Mehmet Yunus Genceroglu +3 more
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Early steps in mitochondrial protein import [PDF]
, 1990 The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Stuart, Rosemary A. +2 more
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Cytochrome c and superoxide [PDF]
JBIC Journal of Biological Inorganic Chemistry, 2013 Wegerich et al. (J. Biol. Inorg. Chem. 18:429-440, 2013), working with singly modified human cytochromes c, claim to have found a new mechanism for the reduction of iron(III) cytochrome c by superoxide. I show that electron transfer by way of the solvent-accessible haem edge - a mechanism not considered by Wegerich et al.
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Mitochondrial DNA variation in the endangered fish Dawkinsia tambraparniei (Actinopterygii: Cypriniformes: Cyprinidae) from southern Western Ghats, India [PDF]
Acta Ichthyologica et Piscatoria, 2014 Background. Dawkinsia tambraparniei (Silas, 1954) is confined to an area not exceeding 100 km2 within a single watershed—the Tamiraparani River, southern Western Ghats, India.
K. Kannan +3 more
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Unfolded States of Heme Proteins [PDF]
, 2010 Cytochromes adopt discrete structures when the heme cofactor is present. Since the heme provides crucial contacts in the native protein, this hydrophobic prosthetic group plays an important role in the folding mechanism and introduces interesting ...
Pribisko Yen, Melanie Anne
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Structure-Function Analysis of the Bifunctional CcsBA Heme Exporter and Cytochrome
mBio, 2018 Although intracellular heme trafficking must occur for heme protein assembly, only a few heme transporters have been unequivocally discovered and nothing is known about their structure or mechanisms.
Molly C. Sutherland +5 more
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Import of cytochrome c into mitochondria. Cytochrome c heme lyase [PDF]
European Journal of Biochemistry, 1987 The import of cytochrome c into mitochondria can be resolved into a number of discrete steps. Here we report on the covalent attachment of heme to apocytochrome c by the enzyme cytochrome c heme lyase in mitochondria from Neurospora crassa. A new method was developed to measure directly the linkage of heme to apocytochrome c. This method is independent
D W, Nicholson, H, Köhler, W, Neupert
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Damage to proteins by peroxidized lipids
Journal of Lipid Research, 1963 The purpose of this research was to determine the mechanism of damage to protein by the free radical intermediates formed during the peroxidation of lipids. The reaction system consisted of linolenic acid, cytochrome c, and oxygen.
I.D. Desai, A.L. Tappel
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Oxygen Activation and Energy Conservation by Cytochrome c Oxidase
Chemical Reviews, 2018 This review focuses on the type A cytochrome c oxidases (CcO), which are found in all mitochondria and also in several aerobic bacteria. CcO catalyzes the respiratory reduction of dioxygen (O2) to water by an intriguing mechanism, the details of which ...
M. Wikström, K. Krab, Vivek Sharma
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Differentiation and cell density upregulate cytochrome c levels in megakaryoblastic cell lines: Implications for analysis of CYCS-associated thrombocytopenia. [PDF]
PLoS ONE, 2017 Mutations in the cytochrome c gene (CYCS) cause autosomal dominant thrombocytopenia by an unknown mechanism. While attempting to generate megakaryoblastic cell lines exogenously expressing cytochrome c variants, we discovered that endogenous cytochrome c
Lily Ong +2 more
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