Results 201 to 210 of about 448,030 (290)

Proton-linked effects on the axial coordination in ferric and ferrous horse heart cytochrome c. [PDF]

open access: yesProtein Sci
Sebastiani F   +8 more
europepmc   +1 more source

Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere   +4 more
wiley   +1 more source

Impact of pulse duration on cardiac electroporation: nanosecond pulses enhance cardiomyocyte selectivity and promote a Raman-detected shift towards apoptotic cell death. [PDF]

open access: yesEuropace
Sowa PW   +10 more
europepmc   +1 more source

Biomedical Applications of Nanozymes: An Enzymology Perspective

open access: yesAngewandte Chemie, EarlyView.
With a lens of enzymology, this review compares nanozymes with enzymes using the Michaelis‐Menten model and differences in KM and kcat along with catalysis in complex biological environment. The implications of these differences in biomedical applications of nanozymes are then described with a statistical analysis of the trend of therapeutic use of ...
Vasily G. Panferov   +4 more
wiley   +2 more sources

THE RÔLE OF THE CYTOCHROMES IN THE ACTION OF “INDOPHENOL OXIDASE”

open access: hybrid, 1938
Elmer Stotz, A.E. Sidwell, T. R. Hogness
openalex   +1 more source

Mechanistic Divergence in Sulfur‐Ligated Iron(III)‐Alkylperoxo Reactivity: Aldehyde Oxidation Prevails over Deformylation

open access: yesAngewandte Chemie, EarlyView.
This study explores the mechanistic investigation into an unusual reactivity of a thioether‐ligated low‐spin Fe(III)‐alkylperoxide with cyclohexane–carboxaldehyde as a mimic of nonheme iron(II) enzyme intermediates and highlights that only efficient catalysis happens from a high‐valent iron(IV)‐oxo species.
Jagnyesh K. Satpathy   +6 more
wiley   +2 more sources

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