Results 201 to 210 of about 391,026 (214)

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

Cell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee, Matthew Phanchana, Phorutai Pearngam, Nopphon Petchyam, Kornkanok Promthep, Ponlawit Wisomka, Suchanoot Kutpruek, Supitcha Pannengpetch, Tanya Prasertporn, Sujira Mukda, Piyarat Govitrapong, Chutikorn Nopparat   +11 more
wiley   +1 more source

Role Assessment of Water-Soluble Pharmaceutical Form of Phosphatidylcholine on the Catalytic Activity of Cytochrome P450 2C9 and 2D6. [PDF]

Int J Mol Sci
Koroleva PI, Bulko TV, Kuzikov AV, Gilep AA, Romashova YA, Tichonova EG, Kostrukova LV, Archakov AI, Shumyantseva VV.   +8 more
europepmc   +1 more source

p38α and p38β regulate osmostress-induced apoptosis. [PDF]

J Biol Chem
Ben Messaoud N, López JM.
europepmc   +1 more source

Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis

Cancer Communications, EarlyView.
Lea Järke, Saskia Weber‐Stiehl, Kensuke Shima, Karlis Arturs Moors, Jerome Genth, Fenja Amrei Schuran, Lena Best, Markus Tschurtschenthaler, Burkhardt Flemer, Silke Lüschen, Christoph Röcken, Andreas Tholey, Christoph Kaleta, Jan Rupp, Philip Rosenstiel, Felix Sommer   +15 more
wiley   +1 more source

Pioneering Women Shaping the Field of Biocatalysis

ChemCatChem, EarlyView.
Groundbreaking works of women scientists in biocatalysis are highlighted in this article. Their innovative contributions are categorized in four interrelated research areas, collectively driving advancements in enzymatic biotransformations. Abstract In this perspective article, we celebrate the accomplishments of female‐led research groups in ...
Ana I. Benítez‐Mateos, Caroline E. Paul, Sandy Schmidt, Martina Letizia Contente   +3 more
wiley   +1 more source

Dioxygen reductase heterogeneity is crucial for robust aerobic growth physiology of Escherichia coli. [PDF]

iScience
Patil AV, Shirsath AM, Anand A.
europepmc   +1 more source

Translational Medicine in Alzheimer's Disease: The Journey of Donanemab From Discovery to Clinical Application

Chronic Diseases and Translational Medicine, EarlyView.
Donanemab, approved by the U.S. FDA in July 2024, targets amyloid plaques in the brain to treat Alzheimer's disease in patients with mild cognitive impairment or mild dementia. ABSTRACT Substantial research has been conducted to identify an efficient treatment for Alzheimer's disease (AD).
Nandhini Jayaprakash, Karthikeyan Elumalai   +1 more
wiley   +1 more source

Mitochondrial dysfunction is a hallmark of woody breast myopathy in broiler chickens. [PDF]

Front Physiol
Greene ES, Chen PR, Walk C, Bedford M, Dridi S.   +4 more
europepmc   +1 more source

Biosynthesis of plant neuroactive alkaloids treating Alzheimer's disease. [PDF]

Front Pharmacol
Yin Q, Zhu Z, Yang M.
europepmc   +1 more source

Redox-Activated Proton Transfer through a Redundant Network in the Q_o Site of Cytochrome <i>bc</i>₁. [PDF]

J Chem Inf Model
Arantes GM.
europepmc   +1 more source