Results 111 to 120 of about 40,950,057 (342)

Cytochrome C Biosensor—A Model for Gas Sensing

Sensors, 2011
This work is about gas biosensing with a cytochrome c biosensor. Emphasis is put on the analysis of the sensing process and a mathematical model to make predictions about the biosensor response.
Gabriele Nelles, Nadejda Krasteva, Ingeborg Hospach, Michael Hulko   +3 more
doaj   +1 more source

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.

Genes & Development, 2000
TNFR1/Fas engagement results in the cleavage of cytosolic BID to truncated tBID, which translocates to mitochondria. Immunodepletion and gene disruption indicate BID is required for cytochrome c release.
M. Wei, T. Lindsten, V. Mootha, S. Weiler, A. Gross, M. Ashiya, C. Thompson, S. Korsmeyer   +7 more
semanticscholar   +1 more source

Hsp27 inhibits cytochromeHsp27 Inhibits Cytochrome c-Mediated Caspase Activation bySequestering Both Pro-caspase-3 and Cytochrome c

, 2001
Mitochondrial cytochrome c release in response to pro-apoptotic signals leads to the formation of a cytochrome c/Apaf-1/procaspase-9 complex (the apoptosome) and resultant activation of caspase-9 and caspase-3.
Samali, A., Concannon, C. G., Orrenius, S.   +2 more
core   +1 more source

Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles

Advanced Science, EarlyView.
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu, Youzhi Xu, Weitao Zhang, Yongyue Ning, Yaojia Jiang, Yongquan Ning, Genping Huang, Jiawei Cheng, Paramasivam Sivaguru, Xihe Bi   +9 more
wiley   +1 more source

Childhood encephalomyopathy with cytochrome c oxidase deficiency, ataxia, muscle wasting, and mental impairment

, 1986
The son of third cousins was normal until age 2 when he had difficulty walking. At age 8 there was limb weakness, ataxia, loss of tendon reflexes, dislalia, and he was mildly retarded.
Vergani L., Angelini C., Rinaldo P., Bet L., Bresolin N., Trevisan C., Pegolo G.   +6 more
core   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Cytochrome c-induced increase of motionally restricted lipid in reconstituted cytochrome c oxidase membranes, revealed by spin-label ESR spectroscopy.

, 1998
Cytochrome c oxidase isolated from beef heart mitochondria was reconstituted in bilayer membranes of the anionic lipid dimyristoylphosphatidylglycerol (DMPG) with varying enzyme/DMPG ratio.
Kleinschmidt, Jörg, Marsh, D., Powell, Gary L., Kleinschmidt, J., Powell, G., Marsh, Derek   +5 more
core   +1 more source

VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast [PDF]

, 2016
Mitochondrial outer membrane permeabilization is a key event in apoptosis processes leading to the release of lethal factors. We have previously shown that absence of the ADP/ATP carrier (AAC) proteins (yeast orthologues of mammalian ANT proteins ...
Côrte-Real, Manuela, Dário Trindade, Maria João Sousa, Sousa, Maria João, Manon, Stephen, Pereira, Clara Isabel Ferreira, Susana R. Chaves, Chaves, Susana Alexandra Rodrigues, Clara Pereira, Stéphen Manon, Manuela Côrte-Real, Trindade, Dario Alexandre Martins   +11 more
core   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Cytochrome c signalosome in mitochondria [PDF]

, 2011
Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the cytoplasmic adducts of cytochrome
Miguel A. De la Rosa, José M. García-Heredia, Irene Díaz-Moreno, Díaz Moreno, Irene, Rosa Acosta, Miguel Ángel de la, García Heredia, José Manuel, Díaz Quintana, Antonio Jesús, Antonio Díaz-Quintana   +7 more
core   +1 more source