Results 91 to 100 of about 28,268,520 (143)

Impact of <i>N</i>-Acetylation on DNA Damage and Oxidative Stress Responses in Mammalian Cells and Human Hepatocytes Treated with Hydralazine. [PDF]

Biomolecules
Habil MR, Stephens MA, Cass AA, Mittlestat EM, Kwon D, Ellison A, Kouokam JC, Hein DW.   +7 more
europepmc   +1 more source

ATTNSOM: learning cross-isoform attention for cytochrome P450 site-of-metabolism prediction. [PDF]

Bioinformatics
Kim H, Lee E, Chung S, Park J, Baek S, Kang J.   +5 more
europepmc   +1 more source

Six-compound cocktail for maturation of human pluripotent stem cell-derived liver spheroids for toxicity prediction. [PDF]

Nat Commun
Tian L, Anas FH, Hasselkus R, Joseph E, Chadraa M, Koç B, Wu W, Karnam B, Flores-Muñoz P, Alon A, Morris J, Bentwich I, Bein A.   +12 more
europepmc   +1 more source

Effects of CYP1A2 genetic polymorphisms on the pharmacokinetics of pentoxifylline and its active metabolites. [PDF]

BMC Pharmacol Toxicol
Guo L, Sun X, Qiu B, Bai W, Du Y, Song H.   +5 more
europepmc   +1 more source

Effects of simulated exogenous and endogenous lipid microenvironments on cannabidiol disposition and cytochrome P450 2C19-mediated drug interactions: New mechanistic insights. [PDF]

Drug Metab Dispos
Nguyen AP, Rotich FC, Cech NB, Paine MF.
europepmc   +1 more source

Developmental exposure to a human-relevant PCB mixture: impacts on PCB congeners, metabolites, and drug-metabolizing enzymes in the bladder of post-weaning mice. [PDF]

Arch Toxicol
Wang H, Goskowicz A, Spiegelhoff A, Kennedy CL, Ridlon MM, Marek RF, Lehmler HJ, Keil Stietz KP.   +7 more
europepmc   +1 more source

Apatinib Inhibits the Metabolic Clearance of Ropivacaine: An in vitro and in vivo Evaluation. [PDF]

Drug Des Devel Ther
Zhang W, Wang P, Cai Y, Feng C, Dong J, Jin Z, Xia F.   +6 more
europepmc   +1 more source

Cytochrome P450 inhibitors: friends or foes? [PDF]

Front Chem
Vyas SK, Ahmed MI, Dixit VA.
europepmc   +1 more source

The novel third-generation antipsychotic drug brexpiprazole affects hepatic transcription factors, serum hormone levels, and cytochrome P450 enzymes after prolonged treatment: pharmacological significance. [PDF]

Pharmacol Rep
Danek PJ, Pukło R, Daniel WA.
europepmc   +1 more source

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug-Metabolizing Enzymes. [PDF]

J Clin Pharmacol
Zhou XJ, Vo A, Morelli G, Montrond M, Lynch S, Pietropaolo K, Belanger B, Good S, Horga A, Agrawal N, Hammond J.   +10 more
europepmc   +1 more source