Results 61 to 70 of about 28,268,520 (143)

Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain [PDF]

, 2009
In low nanomolar concentrations, NO (nitric oxide) functions as a transmitter in brain and other tissues, whereas near-micromolar NO concentrations are associated with toxicity and cell death.
Keynes, R.G., Catherine N. Hall, Robert G. Keynes, Hall, C.N., Garthwaite, J., John Garthwaite   +5 more
core  

Studies on the interaction of NADPH cytochrome P-450 reductase and cytochromes P-450

, 1988
Chemical modification of cytochrome P-450 reductase was used to determine the involvement of charged amino acids in the interaction between the reductase and two forms of cytochrome P-450.
Nadler, Steven Gary
core   +1 more source

The peroxidase properties of cytochrome P-450. [PDF]

, 1973
Linoleic acid hydroperoxide (LAHPO) when incubated with heme compounds or liver microsomes is rapidly decomposed, presumably by a free radical mechanism, to yield a complex range of products.
Hrycay, Eugene George
core   +1 more source

Cytochrome P-450 et métabolisme du chlortoluron. Monooxygénases à cytochrome P-450 chez les plantes

, 1992
Cytochrome P-450 et métabolisme du chlortoluron. Monooxygénases à cytochrome P-450 chez les plantes.
Mougin, Christian
core  

All rights of reproduction in any form reserved. Quinolone Antibacterial Agents: Relationship between Structure and In Vitro Inhibition of the Human Cytochrome P450 Isoform CYP1A2

, 2020
ABBREVIATIONS: CYP1A2, cytochrome P450 isoform CYP1A2; QSAR, quantitative structure-activity relationship; 1 ,7-DMX, 1 ,7 ...
Uwe Fuhr, Eva-Maria Manaut, Fritz Anders, Andre G Chu, Ferran Mahr, Daniel T W Lopez-De-Brinas, A Horst Sanz, Gerhard Pernet, Francesc G#{220}nterstrobl, Elena Sorgel, Staib   +10 more
core  

Cytochrome P-450 in drug-resistant Mycobacterium tuberculosis

, 1999
Methods for the isolation and spectrophotometric determination of cytochrome P-450 in mycobacteria were standardized. Cytochrome P-450 levels were estimated in Mycobacterium tuberculosis organisms sensitive to both isoniazid and rifampicin and resistant ...
Gurumurthy, Prema, Narayanan, PR, Ramachandran, Geetha, Mahadevan, Usha   +3 more
core  

Characterization of a phenobarbital-inducible cytochrome P-450, NADPH-cytochrome P-450 reductase and reconstituted cytochrome P-450 mono-oxygenase system from rat brain. Evidence for constitutive presence in rat and human brain

, 1992
Cytochrome P-450 was purified to apparent homogeneity from the brain microsomes of phenobarbital-treated rats. The specific content of the purified P-450 was 12.7 nmol/mg of protein.
Boyd, M. R., Ravindranath, V., Anandatheerthavarada, H. K.   +2 more
core   +1 more source

Studies on the synthesis of cytochrome P-450 and cytochrome P-448 in rat liver

, 1980
The synthesis of cytochrome P-450 (phenobarbital inducible) and cytochrome P-448 (3-methylcholanthrene inducible) have been studied in rat liver in vivo and in the wheat germ cell-free system using anti-cytochrome P-450 and anti-cytochrome P-448 ...
Padmanaban, G., Kumar, Ashwani
core   +1 more source

Effects of Four Marine Toxins on Murine Hepatic Biotransformation Enzymes. [PDF]

Toxins (Basel)
Soto de Jesus J, González-Keelan C, Meléndez PA, Cadilla CL, Contreras J, Jiménez-Vélez BD.   +5 more
europepmc   +1 more source

Evaluating the Impact of CYP1A2 Inhibition on the Pharmacokinetics of Savolitinib: A Phase 1 Open-Label Study. [PDF]

Pharmacol Res Perspect
Miah K, Reddy J, Sharma P, Igwegbe I, Nelson S, Muldoon C, Goldwater R, Vishwanathan K.   +7 more
europepmc   +1 more source