Results 141 to 150 of about 32,368 (172)

Impact of CYP2D6 genotype on fluoxetine exposure and treatment switch in adults and children/adolescents. [PDF]

Eur J Clin Pharmacol
Nordby KL, Faraj P, Molden E, Hole K.
europepmc   +1 more source

Enhancing CYP2D6 genotyping with nanopore sequencing to address allele diversity P. vivax malaria elimination. [PDF]

Sci Rep
Wongsurawat T, Jenjaroenpun P, Suwannasin K, Wankaew N, Sanguansakpakdee N, Amornpornviwat T, Dondorp AM, Day NPJ, Nosten F, White NJ, Imwong M.   +10 more
europepmc   +1 more source

Proof of principle concept for the analysis and functional prediction of rare genetic variants in the CYP2C19 and CYP2D6 genes. [PDF]

Hum Genomics
Johansson I, Lu Y, Zhou Y, Krebs K, Akcan M, Milani L, Ingelman-Sundberg M.   +6 more
europepmc   +1 more source

Epigenetics in pharmacogenes encoding metabolizing enzymes of second-generation antipsychotics used in schizophrenia and its clinical implications. [PDF]

Front Pharmacol
Alvarado AT, Zavaleta AI, Li-Amenero C, Bendezú MR, Garcia JA, Chávez H, Palomino-Jhong JJ, Surco-Laos F, Laos-Anchante D, Melgar-Merino EJ, Bolarte-Arteaga M, Tasayco-Yataco N, Pariona-Llanos R.   +12 more
europepmc   +1 more source

Analysis of <i>CYP2D6</i> Gene Variant Frequencies in Iranian Population. [PDF]

Iran J Med Sci
Hokmabadi M, Asadifard E, Arbabi-Bidgoli S, Naghavi A, Hasanzad M.   +4 more
europepmc   +1 more source

Building Sub-Saharan African PBPK Populations Reveals Critical Data Gaps: A Case Study on Aflatoxin B1. [PDF]

Toxins (Basel)
Lootens O, De Boevre M, De Saeger S, Van Bocxlaer J, Vermeulen A.   +4 more
europepmc   +1 more source

Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes. [PDF]

Int J Mol Sci
Sakamuru S, Travers J, Klumpp-Thomas C, Huang R, Witt KL, Ferguson SS, Simmons SO, Reif DM, Simeonov A, Xia M.   +9 more
europepmc   +1 more source

Optimizing Nortriptyline Dosing: A Comparison between Pharmacogenetics-Based, Phenotype-Based, and Standard Dosing. [PDF]

Clin Pharmacokinet
Vos CF, Coenen MJH, Ter Hark SE, Schellekens AFA, Aarnoutse RE, Janzing JGE, Ter Heine R.   +6 more
europepmc   +1 more source

<i>CYP2D6</i> polymorphism rs1065852 significantly increases the risk of type 2 diabetes. [PDF]

Ann Med
Wei H, Zhao Q.
europepmc   +1 more source

Investigation of the Relevance of CYP3A4 Inhibition on the Pharmacokinetics of the Novel P2X3 Antagonist Filapixant: Results of In Vitro Explorations and a Fixed-Sequence Clinical Trial with Itraconazole in Healthy Volunteers. [PDF]

Int J Mol Sci
Francke K, Rottmann A, Klein S, Höchel J, Friedrich C.   +4 more
europepmc   +1 more source