PBPK Modeling to Predict Clinical Drug-Drug Interaction and Impact of Hepatic Impairment for an ADC With the Payload Auristatin F-Hydroxypropylamide. [PDF]
CPT Pharmacometrics Syst PharmacolKumar N +8 more
europepmc +1 more source
Effects of drug interactions and liver disease on the pharmacokinetics of ropivacaine [PDF]
, 2003 Jokinen, Mika
core
Effects of mallotus furetianus extract on CYP3A activities in rats. [PDF]
Sci RepHuang W +5 more
europepmc +1 more source
Method development and validation for simultaneous analysis of four bile acids as CYP3A drug-drug interaction biomarkers. [PDF]
BioanalysisXun Z +5 more
europepmc +1 more source
Pharmacokinetics, mass balance, and metabolism of [<sup>14</sup>C]SAF-189s, a potent anaplastic lymphoma kinase/c-ROS proto-oncogene 1 inhibitor in humans: Metabolism potentially affected by interaction of cytochrome P450 enzymes and intestinal microbiota. [PDF]
Drug Metab DisposYang M +10 more
europepmc +1 more source
Investigation of the Relevance of CYP3A4 Inhibition on the Pharmacokinetics of the Novel P2X3 Antagonist Filapixant: Results of In Vitro Explorations and a Fixed-Sequence Clinical Trial with Itraconazole in Healthy Volunteers. [PDF]
Int J Mol SciFrancke K +4 more
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Biological interactions of genotypes with , and in living donor liver transplantation recipients [PDF]
core +1 more source
Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations. [PDF]
Br J Clin PharmacolBaan SD +3 more
europepmc +1 more source
Metabolism of Cannabidiol in Respiratory-Associated Cells and HepG2-Derived Cells and Molecular Docking of Cannabidiol and Its Metabolites with CYP Enzymes and Cannabinoid Receptors. [PDF]
Int J Mol SciTongkanarak K +5 more
europepmc +1 more source
Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat. [PDF]
Br J Clin Pharmacolvan Ton AMP +4 more
europepmc +1 more source