BACKGROUND AND OBJECTIVE: Acetaminophen overdose is the most frequent cause of liver injuries. N-acetyl-p-benzoquinone imine (NAPQI) has been proposed as the toxic metabolite of acetaminophen induced by cytochrome P-450.
MT Kazemi +8 more
doaj
Tung, Norint P., Ma, Joseph D.
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Population Pharmacokinetic Model Assessment of the Effects of Body Weight on Risk of Drug-Drug Interactions After Posaconazole Discontinuation. [PDF]
Wrishko RE +3 more
europepmc +1 more source
Comments to the Article Wu Y, Völler S, Goulooze SC, et al. A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite. J Clin Pharmacol. 2025;65(12):1829-1843. doi: 10.1002/jcph.70080. PMID: 40910464; PMCID: PMC12649303. [PDF]
Pasanen M, Juvonen RO.
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Brewing an Interaction: Non-commercial Green Tea-Associated Supratherapeutic Tacrolimus Levels Presenting With Gastrointestinal Symptoms. [PDF]
Modi R, Patel F, Chag A, Joshi MR.
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A Clinically Relevant Drug Interaction Between Busulfan and Rifampin in the Setting of Hematopoietic Stem Cell Transplant Conditioning. [PDF]
Drangines C, Laquet J, Kunwor R.
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Clinical Evaluation of Drug-Drug Interactions With Aficamten. [PDF]
Maharao N +11 more
europepmc +1 more source

