Results 51 to 60 of about 5,186 (110)

Ribociclib is not a substrate or inhibitor of Oatp1b-mediated uptake in vivo. [PDF]

Cancer Chemother Pharmacol
Drabison T, Ahmed EA, Colasanti N, Weber RH, Sparreboom A, Eisenmann ED.   +5 more
europepmc   +1 more source

Evaluation of Drug-Drug Interaction Potential Between the Oral Antibiotic Zoliflodacin and the CYP3A4 Inhibitor Itraconazole: A Phase 1 Study in Healthy Participants. [PDF]

Clin Transl Sci
Luckey A, Larson KB, Rayad N, Heep M, Delhomme S, Kornmann G, Mueller JP, O'Donnell JP, O'Brien S, Fuhr R, Gillon JY.   +10 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling of Valemetostat to Inform Dose Recommendations When Coadministered With CYP3A/P-gp Modulators. [PDF]

Clin Transl Sci
Watanabe A, Okudaira N, Tachibana M, Kazui M, Kotsuma M, Shimizu T, Lau Y.   +6 more
europepmc   +1 more source

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug-Metabolizing Enzymes. [PDF]

J Clin Pharmacol
Zhou XJ, Vo A, Morelli G, Montrond M, Lynch S, Pietropaolo K, Belanger B, Good S, Horga A, Agrawal N, Hammond J.   +10 more
europepmc   +1 more source

Pharmacokinetic Drug-Drug Interaction Potential of Oral Anticancer Drugs. [PDF]

Clin Pharmacol Ther
Alhurayri F, Younis IR, Jalal SI, Logan TF, Maniar R, Bray SM, Quinney SK, Desta Z, Skaar TC, Tisdale JE, Shugg T.   +10 more
europepmc   +1 more source

Evaluation of the cytochrome P450-mediated drug interaction profile of olorofim. [PDF]

Antimicrob Agents Chemother
Cornelissen K, Rex JH, Zinzi D, Law D, Upcott Gill R, Jones HM, Maertens J, Chen SC-A, Brüggemann R.   +8 more
europepmc   +1 more source

Label-Free High-Throughput Screening of CYP3A4 Inhibitors Using Acoustic Ejection Mass Spectrometry. [PDF]

Anal Chem
Rimmer MA, Wang J, Ranathunge TA, Shi Z, Li Y, Lee D, Chai SC, Lin W, Twarog NR, Ansari AZ, Shelat AA, Young BM, Chen T, Yang L.   +13 more
europepmc   +1 more source

Effect of Valemetostat on the Pharmacokinetics of Midazolam and Digoxin: A Phase 1 Drug-Drug Interaction Study in Patients With Non-Hodgkin Lymphoma. [PDF]

Clin Transl Sci
Tachibana M, Horwitz S, Jacobsen E, Foss F, Allen P, Porcu P, Feldman T, Ruan J, Brammer JE, Wang J, Inaba S, Iko Y, Nakajima K, Kakurai Y, Kitami N, Chen Y, Lau Y.   +16 more
europepmc   +1 more source

The effect of salidroside, an active component of Rhodiola rosea, on the metabolic activity of rat and human cytochromes P450 in preclinical studies. [PDF]

Pharmacol Rep
Klaskova E, Jurica J, Danek PJ, Mlcuchova N, Eyrilmez SM, Borilova Linhartova P, Bednar D, Kamaraj R, Daniel WA, Zendulka O.   +9 more
europepmc   +1 more source

Genotype-Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers. [PDF]

Clin Transl Sci
Etkins J, So GC, Lu JBL, Koyama S, Gisch DL, Melo Ferreira R, Cheng YH, McClara K, Jun J, Miller M, Desta Z, Eadon MT.   +11 more
europepmc   +1 more source