Effect of Testosterone Therapy on Cytochrome P450 3A and P-Glycoprotein Activities Using Midazolam and Digoxin as Probe Substrates Among Transgender Adults. [PDF]
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Physiologically Based Pharmacokinetic Modeling in Patients With Hepatic Impairment: Are Changes in Bosutinib Exposure Profiles Driven by Altered Absorption or Distribution? [PDF]
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Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity. [PDF]
Front PharmacolFashe MM +8 more
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Effect of Rifampicin on the Pharmacokinetics of Valemetostat and Its Primary Metabolite: A Phase 1 Study in Healthy Participants. [PDF]
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Impact of CFTR modulator concentrations on clinical response in cystic fibrosis. [PDF]
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Managing Drug-Drug Interactions Involving the Non-Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling. [PDF]
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In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes. [PDF]
Bull Math BiolKahiya ET +5 more
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Analysis of interactions between posaconazole/voriconazole and venetoclax. [PDF]
Antimicrob Agents ChemotherLiu C +8 more
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1β-Hydroxydeoxycholic acid as an endogenous biomarker in human plasma for assessment of drug-drug interaction with moderate CYP3A inhibitor. [PDF]
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Comparative Analysis of Isavuconazole DDIs With Other Azole Antifungal Drugs and PBPK Model-Informed Dosing Recommendations for Anticancer Drugs. [PDF]
CPT Pharmacometrics Syst PharmacolGoosen TC +6 more
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