Results 11 to 20 of about 102,281 (237)

Role of phospholipid in electron transfer in a reconstituted liver microsomal enzyme system containing cytochrome P-450 [PDF]

Chemico-Biological Interactions, 1971
Abstract Phosphatidylcholine, which is required for fatty acid, hydrocarbon and drug hydroxylation in a reconstituted liver microsomal enzyme system, is essential for the enzymatic reduction of cytochrome P-450.
Coon, Minor J., Autor, Anne P., Strobel, Henry W.   +2 more
openaire   +5 more sources

Canadine synthase from Thalictrum tuberosum cell cultures catalyses the formation of the methylenedioxy bridge in berberine synthesis [PDF]

, 1994
An enzyme system catalysing the formation of the methylenedioxy bridge at ring A of (S)-canadine [ = (S)-tetrahydroberberine] from (S)-tetrahydrocolumbamine has been detected in microsomal preparations from different Ranunculaceae and Berberidaceae cell ...
Rüffer, Martina, Zenk, Meinhart H.
core   +2 more sources

Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation

Biomedicines, 2021
This study evaluates the effects of chronic treatment with EET-A, an orally active epoxyeicosatrienoic acid (EETs) analog, on the course of aorto-caval fistula (ACF)-induced heart failure (HF) in Ren-2 transgenic rats (TGR), a model characterized by ...
Petr Kala, Matúš Miklovič, Šárka Jíchová, Petra Škaroupková, Zdeňka Vaňourková, Hana Maxová, Olga Gawrys, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, John D. Imig, John R. Falck, Josef Veselka, Luděk Červenka, Renáta Aiglová, Marek Vícha, Vít Gloger, Miloš Táborský   +16 more
doaj   +1 more source

Comparison of clinical pharmacology of voriconazole and posaconazole

Contemporary Oncology, 2016
Despite greater knowledge and possibilities in pharmacotherapy, fungal infections remain a challenge for clinicians. As the population of immunocompromised patients and those treated for their hematologic ailments increases, the number of fungal ...
Beata M. Sienkiewicz, Łukasz Łapiński, Anna Wiela-Hojeńska   +2 more
doaj   +1 more source

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W., Ashwell M., Beattie D. S., Beattie D. S., Brunner G., Burstone M. S., Davis K. A., Delbruck A., Fiske C. H., Folch J., Gear A. R. L., Gear A. R. L., Gear A. R. L., Gelder B. F., Gotterer G. S., Hasegawa E., Hawley E. S., Johnson A. B., Klingenberg M., Kuntzel H., Labbe R. F., Lentz P. E., Neupert W., Neupert W., Novikoff A. B., Ohnishi K., Omura T., Parsons D. F., Parsons D. F., Pette D., Pollak J. K., Pullmann M. E., Raw J., Raw J., Reith A., Schneider W. C., Schuel H., Schumacher H.-H., Sebald W., Sebald W., Seligman A. M., Sies H., Sottocasa G. L., Stoffel W., Strecker H. J., Swick R. W., Szarkowska L., Tabor C. W., Tol A., Vazquez J. J., Yonetani T.   +50 more
core   +1 more source

Comparison of Cholesterol Lowering Diets: Apple, Casein Cytochrom P450 protein and Cholesterol 7α Hydroxylase Activities in Hamsters [PDF]

, 2010
Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement.
Rakesh Sharma, Rakesh K. Tandon
core   +2 more sources

Antioxidant Activity of New Aramide Nanoparticles Containing Redox-Active <em>N</em>-phthaloyl Valine Moieties in the Hepatic Cytochrome P₄₅₀ System in Male Rats

Molecules, 2012
We report the synthesis of aramide nanoparticles containing a chiral <em>N</em>-phthaloyl valine moiety and their antioxidant activities on hepatic contents of cytochrome P₄₅₀, amidopyrene <em>N</em> ...
Hammed H. A. M. Hassan, Sabah G. El-Banna, Amel F. Elhusseiny, El-Sayed M. E. Mansour   +3 more
doaj   +1 more source

Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing

Frontiers in Pharmacology, 2022
Caffeine is by far the most ubiquitous psychostimulant worldwide found in tea, coffee, cocoa, energy drinks, and many other beverages and food. Caffeine is almost exclusively metabolized in the liver by the cytochrome P-450 enzyme system to the main ...
Jan Grzegorzewski, Florian Bartsch , Adrian Köller, Matthias König   +3 more
doaj   +1 more source

In Vivo Evolution of Butane Oxidation by Terminal Alkane Hydroxylases AlkB and CYP153A6 [PDF]

, 2009
Enzymes of the AlkB and CYP153 families catalyze the first step in the catabolism of medium-chain-length alkanes, selective oxidation of the alkane to the 1-alkanol, and enable their host organisms to utilize alkanes as carbon sources.
Arnold, Frances H., Chen, Mike M., Koch, Daniel J., van Beilen, Jan B.   +3 more
core   +3 more sources

Medicinal importance of grapefruit juice and its interaction with various drugs

Nutrition Journal, 2007
Grapefruit juice is consumed widely in today's health conscious world as a protector against cardiovascular diseases and cancers. It has however, been found to be an inhibitor of the intestinal cytochrome P – 450 3A4 system, which is responsible for the ...
Imam Sardar Z, Kiani Jawad
doaj   +1 more source