Dimethylnitrosamine demethylation by reconstituted liver microsomal cytochrome P-450 enzyme system [PDF]
Biochemical Journal, 1975 Oxidative demethylation of dimethylnitosamine was studied with both reconstituted and unresolved liver microsomal cytochrome P-450 enzyme systems from rats and hamsters. Proteinase treatment of liver microsomal preparations yielded cytochrome P-450 particulate fractions.
P D, Lotlikar, W J, Baldy, E N, Dwyer
openaire +2 more sources
Transcriptome profiling of a spirodiclofen susceptible and resistant strain of the European red mite Panonychus ulmi using strand-specific RNA-seq [PDF]
, 2015 Background: The European red mite, Panonychus ulmi, is among the most important mite pests in fruit orchards, where it is controlled primarily by acaricide application.
Bajda, Sabina +6 more
core +17 more sources
Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-Ultraviolet A (PUVA) sensitivity [PDF]
, 2013 Background: There are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis.
Deeni, Yusuf Y. +4 more
core +8 more sources
Preparation of Neurospora crassa mitochondria [PDF]
, 1978 The fungus Neurospora crassa represents a eukaryotic cell with high biosynthetic activities. Cell mass doubles in 2-4 hr during expone ntial growth , even in simple salt media with sucrose as the sole carbon source. The microorgani sm forms a mycelium of
Jacki +11 more
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Effects of heme oxygenase isozymes on Leydig cells steroidogenesis [PDF]
, 2009 In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known HO inducer, hemin, increased
Besio Moreno, Marcos Alberto +6 more
core +1 more source
Polymethoxylated flavonoids in citrus fruits: absorption, metabolism, and anticancer mechanisms against breast cancer [PDF]
PeerJPolymethoxylated flavonoids (PMFs) are a subclass of flavonoids found in citrus fruits that have shown multifunctional biological activities and potential anticancer effects against breast cancer.
Yiyu Wang +4 more
doaj +2 more sources
Sites of Biosynthesis of Outer and Inner Membrane Proteins of Neurospora crassa Mitochondria [PDF]
, 1970 Outer and inner membranes of Neurospora crassa mitochondria were separated by the combined swelling, shrinking, sonication procedure. Membranes were characterized by electron microscopy and by marker enzyme activities.
Aasen A. J. +14 more
core +1 more source
Induction of Microsomal Liver Enzymes by Silymarin in Experimental Animals
مجلة كلية الطب, 2011 Background: previous researches showed that the hepatoprotective effect of silymarin was through inhibition of cytochrome p450- system (e.g. protection against Amanita toxin), in addition to protection from free radicals generated by this enzymatic ...
Bahir A.R. Mshiemish +2 more
doaj +1 more source
ADMET and DMPK, 2016 The metabolic syndrome in HIV infected patients is particularly associated with the use protease inhibitors. Atazanavir is an inhibitor of the cytochrome P 450 (CYP) system, in particular CYP3A4 and CYP2C9 which can affect the metabolism of several drugs.
Thirumal Eswara Goud +3 more
doaj +1 more source
Processing peptidase of Neurospora mitochondria [PDF]
, 1984 Subunit 9 (dicyclohexylcarbodiimide binding protein, 'proteolipid') of the mitochondrial F1F0-ATPase is a nuclearly coded protein in Neurospora crassa.
Neupert, Walter +3 more
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