Results 211 to 220 of about 102,281 (237)

The Cytochrome P-450 Drug Metabolizing Enzyme System

Journal of Head Trauma Rehabilitation, 2002
Bruno, Wroblewski, Mel B, Glenn
openaire   +2 more sources

Selective damage of ethanol to cytochrome P-450 enzyme system in alcoholics

Journal of Hepatology, 1989
D. von Knebel, E. Lotterer, U. Foelsch, F.E. Bauer, J. Bircher   +4 more
openaire   +1 more source

A spin trap study on anaerobic dehalogenation of halothane by a reconstituted liver microsomal cytochrome P-450 enzyme system.

Journal of biochemistry, 1982
In the presence of a spin trapping reagent, N-tert-butyl-alpha-phenylnitrone, anaerobic incubation of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) with a reconstituted cytochrome P-450 enzyme system of rabbit liver microsomes exhibited an electron spin resonance spectrum containing signals of a nitroxide radical, and all components of the ...
K, Fujii, N, Miki, M, Kanashiro, R, Miura, T, Sugiyama, M, Morio, T, Yamano, Y, Miyake   +7 more
openaire   +1 more source

[Effect of induction of enzymes of the cytochrome p-450 system on the survival of rats after acute hemorrhage].

Patologicheskaia fiziologiia i eksperimental'naia terapiia, 1996
The effect of acute hemorrhage on the functional status of microsomal cytochrome P-450-dependent hepatic monoxygenases and the impact of induction of these monoxygenases on the survival of posthemorrhagic male Wistar rats. Acute blood loss of the rats, which caused 50% deaths led approximately to a double decrease in the hepatic activity of 77 ...
E I, Astashkin, A Z, Prikhod'ko, A I, Matiushin   +2 more
openaire   +1 more source

Bioorganotin chemistry: a commentary on the reactions of organotin compounds with a cytochrome P-450 dependent monooxygenase enzyme system.

Neurotoxicology, 1984
The biological oxidation of several tributyltin derivatives, by a cytochrome P-450 dependent monooxygenase enzyme system with reduced nicotinamideadeninedinucleotidephosphate as the essential cofactor, produced carbon-hydroxylated compounds identified as alpha-, beta-, gamma- and delta-hydroxybutyldibutyltin derivatives.
openaire   +1 more source

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA

Lancet, The, 1990
Joseph C Kolars
exaly  

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

Nature, 1991
David S Bredt, Paul M Hwang, Charles Julian Lowenstein   +2 more
exaly  

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

New England Journal of Medicine, 2009
Marc S Sabatine
exaly  

Ruthenium catalyzed biomimetic oxidation in organic synthesis inspired by cytochrome P-450

Chemical Society Reviews, 2008
Shun-Ichi Murahashi
exaly  

Cytochrome P-450 and chloroperoxidase: thiolate-ligated heme enzymes. Spectroscopic determination of their active-site structures and mechanistic implications of thiolate ligation

Chemical Reviews, 1987
John H Dawson
exaly