Results 241 to 250 of about 42,048 (270)
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The Cytochrome P-450 Drug Metabolizing Enzyme System

Journal of Head Trauma Rehabilitation, 2002
Bruno, Wroblewski, Mel B, Glenn
openaire   +2 more sources

Selective damage of ethanol to cytochrome P-450 enzyme system in alcoholics

Journal of Hepatology, 1989
D. von Knebel   +4 more
openaire   +1 more source

[Alteration of the lipid composition of rat liver microsomes on reconstitution of the cytochrom P-450 system. Inactivation of the enzyme by lysolecithin].

Biokhimiia (Moscow, Russia), 1977
The lipid composition of rat liver microsomes, their "ghosts" and the reconstituted membrane hydroxylation system was investigated. The phospholipid content and composition of the reconstituted membranes were found to depend on the reconstitution method. The reconstituted membranes contained besides phospholipids also cholesterol and gangliosides.
E V, Diatlovitskaia   +4 more
openaire   +1 more source

[Effect of modifiers of the cytochrome P-450-dependent enzyme system of the liver on the metabolic pathways of diethylnitrosamine activation and inactivation].

Voprosy onkologii, 1987
Pretreatment of Wistar male rats with antioxidants prevented the toxic effect of diethylnitrosamine (DENA) at LD50. Six-fold acceleration of DENA excretion and significant increase of maximum plasma concentration of a DENA metabolite nitrite were, also observed after antioxidants treatment. Liver microsomal metabolism of DNA was altered by pretreatment
T S, Shuliakovskaia   +4 more
openaire   +1 more source

Bioorganotin chemistry: a commentary on the reactions of organotin compounds with a cytochrome P-450 dependent monooxygenase enzyme system.

Neurotoxicology, 1984
The biological oxidation of several tributyltin derivatives, by a cytochrome P-450 dependent monooxygenase enzyme system with reduced nicotinamideadeninedinucleotidephosphate as the essential cofactor, produced carbon-hydroxylated compounds identified as alpha-, beta-, gamma- and delta-hydroxybutyldibutyltin derivatives.
openaire   +1 more source

Estrogen synthetase (aromatase). The cytochrome P-450 component of the human placental enzyme is a glycoprotein

Molecular and Cellular Endocrinology, 1991
Francis L Bellino   +2 more
exaly  

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