Results 161 to 170 of about 506,903 (380)

Cytochrome P450

Definitions, 2020
D. Hoyer, Eric P. Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, N. Simola, James D. Lane, Michael M Morgan, M. Christie, Cecilia J. Hillard, A. Budney, Ryan G. Vandrey, Trevor W. Robbins, P. Nencini, M. Milella, Naheed (Max) Mirza, V. L. Harvey, T. Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, D. Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, R. Depue, Christof Baltes, T. Mueggler, Markus Rudin, Peter J Flor, I. Neumann, Craig A. Erickson, D. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Etienne Sibille, Nicole M. Edgar, Malcolm Lader, Theodora Duka, E. Childs, B. Hahn, Jaanus Harro, P. Newhouse, H. Wilkins, Y. Alici, William Breitbart, Eric Nestler, A. Isles, Lawrence S. Wilkinson, Subhash Pandey, S. Siris, P. Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J. Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, K. Wolff, A. Padhi, N. Fineberg, Warren H. Meck, Catalin V. Buhushi, Lance R. McMahon, Y. Chudasama, Michael Kuhar, J. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, R. Hurst, Michael Bloch, J. F. Leckman, B. J. Sahakian, S. Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, I. Hindmarch, Alyson J. Bond, Jaime M Monti, D. Christensen, Warren K. Bickel, M. Bubar, Kathryn A. Cunningham, Christine A. Franco, M. Potenza, M. López-Ibor, J. López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, M. Palmatier, Rick A. Bevins, Thomas M. Tzschentke, David Roberts, S. Anagnostaras, J. Sage, Stephanie A. Carmack, Steve Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, O. Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, P. V. Migues, A. Christopoulos, Gregory D Stewart, P. Sexton, Y. Shaham, Sunila G Nair, Sarah H. Heil, S. Sigmon, Stephen T. Higgins, Sarah H. Heil, S. Sigmon, Marc N. Branch, Mary Cain, M. Bardo, Robert L. Balster, Sharon Walsh, R. de Rijk, Ronald De Kloet, C. Bourke, Michael J. Owens, C. Viollet, J. Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, C. Bourke, Hamish Mcallister-Williams, A. Marneros, Rodrigo Andrade, I. Izquierdo, L. Bevilaqua, Martin Cammarota, Christoph Hiemke, M. Colado, Richard Green   +148 more
semanticscholar   +3 more sources

Identification of Pyrrolizilactone Biosynthetic Gene Cluster with Unique Short‐Chain Dehydrogenase Gene for 3‐Methylproline Formation

ChemistryEurope, EarlyView.
A standalone enzyme, derived from the reductase domain of a polyketide synthase‐nonribosomal peptide synthetase hybrid enzyme, is identified as a pyrroline carboxylate reductase. This enzyme is involved in the biosynthesis of 3‐methylproline, an amino acid building block of a unique tricyclic pyrrolizidinone structure of a fungal metabolite ...
Naoki Kato, Sayaka Hirosawa, Toshihiko Nogawa, Kiyomi Kinugasa, Tohru Taniguchi, Hiroyuki Osada, Shunji Takahashi   +6 more
wiley   +1 more source

Expresión diferencial de genes en Pyropia columbina (Bangiales, Rhodophyta) bajo hidratación y desecación natural [PDF]

, 2013
Indexación: Web of Science; Scielo.RESUMEN. En Zonas Costeras rocosas, la desecación es gatillada porción Cambios Diarios en los Niveles de marea, y la Evidencia indica experimental de Me Distribución de las algas en la zona intermareal no está ...
Contreras-Porcia, Loretto, Correa, Juan A., Fierro, Camila, Flores-Molina, María Rosa, Guajardo, Eduardo, Kube, Michael, Lovazzano, Carlos, López-Cristoffanini, Camilo, Núñez, Alejandra, Reinhardt, Richard, Thomas, Daniela   +10 more
core  

Evaluation of exposure‐response‐safety relationship of model‐informed low‐dose 500 mg abiraterone acetate in prostate cancer patients

Cancer Communications, EarlyView.
Edmund Chiong, Ziteng Wang, Eleanor Jing Yi Cheong, Yi Chen Yao, Sin Mun Tham, Revathi Periaswami, Poh Choo Toh, Ziting Wang, Qing Hui Wu, Woon Chau Tsang, Arshvin Kesavan, Alvin Seng Cheong Wong, Patrick Thomas Wong, Felicia Lim, Shuaibing Liu, Eric Chun Yong Chan   +15 more
wiley   +1 more source

Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets

The Canadian Journal of Chemical Engineering, EarlyView.
Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou, Georgia Gatidou, Athanasios S. Stasinakis, Michail S. Fountoulakis   +3 more
wiley   +1 more source

Rational and semi-rational engineering of cytochrome P450s for biotechnological applications

Synthetic and Systems Biotechnology, 2018
The cytochrome P450 enzymes are ubiquitous heme-thiolate proteins performing regioselective and stereoselective oxygenation reactions in cellular metabolism.
Lian-Hua Xu, Yi-Ling Du
doaj  

The nitrite anion: the key intermediate in alkyl nitrates degradative mechanism. [PDF]

, 2007
Alkyl nitrates, _in vivo_, are metabolized to yield nitric oxide, and thiol groups are considered necessary cofactors. This statement is based on studies that underline how these species potentiate hemodynamic responsiveness to nitrates in patients with ...
Loris Grossi
core   +1 more source

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

ChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi, Nicoletta Basilico, Erika Iervasi, Chiara Brullo, Silvia Parapini, Marco Ponassi, Camillo Rosano, Andrea Spallarossa   +7 more
wiley   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

A simple and rapid method to measure cholesterol binding to P450s and other proteins

Journal of Lipid Research, 2005
Cholesterol plays an important role in cellular function and membrane compartmentalization and is involved in the interaction with more than a dozen of different proteins. Using three cholesterol-metabolizing cytochrome P450s (P450s 7A1, 46A1, and 11A1),
Natalia Mast, Irina A. Pikuleva
doaj