Results 111 to 120 of about 139,090 (361)

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

open access: yesAdvanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su   +10 more
wiley   +1 more source

Sulfite: Cytochrome \u3cem\u3ec\u3c/em\u3e Oxidoreductase from \u3cem\u3eThiobacillus novellus\u3c/em\u3e [PDF]

open access: yes, 2000
Direct oxidation of sulfite to sulfate occurs in various photo- and chemotrophic sulfur oxidizing microorganisms as the final step in the oxidation of reduced sulfur compounds and is catalyzed by sulfite:cytochrome c oxidoreductase (EC1.8.2.1).
Bennett, Brian   +6 more
core   +1 more source

Cytochromes c550, c552, c1 in the electron transport network of Paracoccus denitrificans: redundant or subtly different in function? [PDF]

open access: yes, 2001
Paracoccus denitrificans strains with mutations in the genes encoding the cytochrome c550, c552, or c1 and in combinations of these genes were constructed, and their growth characteristics were determined.
Ludwig, B.   +5 more
core   +3 more sources

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

open access: yesAdvanced Science, EarlyView.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou   +5 more
wiley   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

open access: yesAdvanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo   +15 more
wiley   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes Р-450 and b5 levels in a rat’s liver under introduction of cobalt and mercury chlorides

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2006
Influence of the cobalt chloride and mercury chloride on the activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes level in a rat’s liver was studied after 0.5, 2 and 14 hours of introduction.
G. V. Ganusova
doaj   +1 more source

Cytochrome P450associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae. [PDF]

open access: yes, 2016
The role of cuticle changes in insecticide resistance in the major malaria vector Anopheles gambiae was assessed. The rate of internalization of 14C deltamethrin was significantly slower in a resistant strain than in a susceptible strain.
Anthousi, Amalia   +14 more
core   +4 more sources

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