Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra+4 more
wiley +1 more source
The role of CsrA in controls the extracellular electron transfer and biofilm production in <i>Geobacter sulfurreducens</i>. [PDF]
Hernández-Eligio A+5 more
europepmc +1 more source
Drug–drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450
Aims To assess the effect of a potent cytochrome P450 (CYP) 3A inhibitor and CYP inducer on the pharmacokinetics of ritlecitinib, a JAK3/TEC family kinase inhibitor, and assess the effect of ritlecitinib on the pharmacokinetics of CYP substrates (midazolam, efavirenz, tolbutamide, caffeine and oral contraceptives [ethinyl oestradiol and levonorgestrel])
Vivek S. Purohit+6 more
wiley +1 more source
Flavonoids and Furanocoumarins Involved in Drug Interactions. [PDF]
Berteina-Raboin S.
europepmc +1 more source
A Bacterial Diphosphopyridine Nucleotide-Linked Cytochrome c Reductase
Arnold F. Brodie
openalex +1 more source
Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations
Aims Voriconazole is extensively metabolized via cytochrome P450 (CYP) enzymes, predominantly CYP2C19 and CYP3A4. Drugs influencing the activity or expression of CYP enzymes can cause clinically relevant changes in the metabolism and voriconazole exposure. Metamizole is known to induce CYP3A4 and CYP2C19.
Simone D. Baan+3 more
wiley +1 more source
Anaerobic corrosion of steel wire by <i>Geoalkalibacter ferrihydriticus</i> under alkaline autotrophic conditions. [PDF]
Zavarzina DG+9 more
europepmc +1 more source
Pharmacology and relevant drug interactions of metamizole
Metamizole is a frequently prescribed analgesic because of its favourable benefit/risk ratio compared with classic NSAIDs. However, increasing research shows that metamizole displays several drug interactions that are relevant to clinical practice. We reviewed the literature to summarize the pharmacology and most clinically relevant drug interactions ...
David J. Brinkman+3 more
wiley +1 more source
Raman microscopy of cryofixed biological specimens for high-resolution and high-sensitivity chemical imaging. [PDF]
Mizushima K+12 more
europepmc +1 more source