Results 191 to 200 of about 19,718,861 (281)

Probing biofilm development, stress response and heterogeneity-spectroscopic characterization of single and multi-species consortia. [PDF]

NPJ Biofilms Microbiomes
Yunda E, Hagberg A, Duteil T, Francius G, Gorzsás A, Quilès F, Ramstedt M.   +6 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire, Andrew T. Lambarth, Ayesha Saleem, Daniel R. Burrage   +3 more
wiley   +1 more source

Chelidonic acid attenuates 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis by modulating oxidative stress and detoxification pathways in Golden Syrian hamsters. [PDF]

J Oral Biol Craniofac Res
Krishnan H, Sivasankaran SM, Balasubramaniyan V, Radhakrishnan MN, Manoharan S.   +4 more
europepmc   +1 more source

The determinants of stability and folding in evolutionarily diverged cytochromes c. [PDF]

J Mol Biol, 2009
Thielges MC, Zimmermann J, Dawson PE, Romesberg FE.   +3 more
europepmc   +1 more source

Warfarin time in therapeutic range of primary healthcare patients in the Western Cape Province, South Africa

British Journal of Clinical Pharmacology, EarlyView.
Introduction Warfarin therapy is the mainstay of anticoagulation treatment in South Africa and requires frequent INR monitoring due to interindividual patient variability. Time in therapeutic range (TTR) reflects the proportion of total treatment time during which INR values are within therapeutic range.
Masudah Paleker, Christopher Kelly, Robin Dyers, Eric Decloedt   +3 more
wiley   +1 more source

Electrochemiluminescence microscopy for real-time, single-cell imaging of surface charge in electroactive bacteria. [PDF]

Nat Commun
Xing Z, Zhang Z, Liu R, Zhuang J, Gou X, Jiang LP, Ma C, Zhu JJ, Chen Z.   +8 more
europepmc   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Cytochrome nanowires under electron microscopy. [PDF]

Emerg Top Life Sci
Petersen HA, Hochbaum AI, Bond DR, Wang F.   +3 more
europepmc   +1 more source