CD19-negative relapse with an apparent cytogenetic shift after blinatumomab-induced measurable residual disease clearance in Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia. [PDF]
Saburi M +5 more
europepmc +1 more source
Summary Complete remission (CR) rates for patients with acute myeloid leukaemia (AML) treated with intensive chemotherapy (IC) have increasingly improved. Yet, relapse remains a concern with a dismal prognosis. In this report, results are presented of a retrospective analysis comparing salvage therapy based on intermediate (I) or high (H)‐dose ...
Pierre‐Yves Dumas +22 more
wiley +1 more source
Spontaneous regression of B-cell acute lymphoblastic leukemia with PAX5 alterations at relapse: a case report. [PDF]
Lesan V, Bittenbring J, Altmeyer S.
europepmc +1 more source
Treatment patterns and clinical outcomes in chronic myeloid leukemia treated with second-line nilotinib-association of molecular milestones and prognostic scores with deep molecular response: a real-world retrospective cohort study. [PDF]
Ćojbašić I +2 more
europepmc +1 more source
Molecular heterogeneity and prognostic biomarkers in primary meningeal melanocytic tumors
Integrated molecular profiling reveals biological heterogeneity among primary meningeal melanocytic tumors, identifying intermediate‐grade PMMT subgroups with distinct recurrence risk. Molecular alterations including SF3B1 mutations and chromosome 8q gains support prognostic stratification, while PRKAR1A alterations and chromosome 17/21q losses aid ...
Rosina Paterra +6 more
wiley +1 more source
Array comparative genomic hybridisation in haematological malignancies: A comprehensive review. [PDF]
Ellaithi MMH, Osman HA.
europepmc +1 more source
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar +12 more
wiley +1 more source
An integrated AI pipeline for automated cytogenetic analysis of bone marrow karyograms in hematological malignancies: A Pix2Pix enhancement and deep learning detection approach. [PDF]
Alsubaie L +4 more
europepmc +1 more source
ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee +3 more
wiley +1 more source

