Results 241 to 250 of about 129,688 (299)
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Cytogenetics and molecular cytogenetics in prenatal diagnosis
Clinics in Laboratory Medicine, 2003Prenatal chromosome diagnosis has been a rapidly changing field over the past 10 years for both sampling methodologies and molecular techniques to complement chromosome analysis. This review summarizes current techniques used by the clinician and their risks, and selected aspects of cytogenetic and molecular techniques used by the laboratories.
Alan E, Donnenfeld, Allen N, Lamb
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Cytogenetics and molecular cytogenetics in multiple myeloma
European Journal of Cancer, 2006Multiple myeloma (MM) is characterized by frequent and complex genomic abnormalities that not only essentially contribute to the pathogenesis of this disease but also reflect its prognostic heterogeneity. There is evidence for two more or less mutually exclusive oncogenic pathways in the early development of clonal plasma cell disorders.
Peter, Liebisch, Hartmut, Döhner
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British Medical Bulletin, 1961
May I begin by recalling that at the Copenhagen Conference five years ago, Tjio and Levan had just published their almost apologetic announcement that they could only find 46 chromosomes in cultured human somatic cells, and Hamerton and I presented evidence that there were 23 bivalents in spermatocytes, not 24.Since that time there has been a very ...
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May I begin by recalling that at the Copenhagen Conference five years ago, Tjio and Levan had just published their almost apologetic announcement that they could only find 46 chromosomes in cultured human somatic cells, and Hamerton and I presented evidence that there were 23 bivalents in spermatocytes, not 24.Since that time there has been a very ...
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American Journal of Obstetrics and Gynecology, 1977
The advantage of a standardized nomenclature is apparent in any discipline. A standardized method for designating carbon molecules in steroid chemistry facilitates communication in endocrinology; consistent staging methods permit comparison of data in oncology.
J L, Simpson, A O, Martin
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The advantage of a standardized nomenclature is apparent in any discipline. A standardized method for designating carbon molecules in steroid chemistry facilitates communication in endocrinology; consistent staging methods permit comparison of data in oncology.
J L, Simpson, A O, Martin
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Methodologies in cancer cytogenetics and molecular cytogenetics
American Journal of Medical Genetics, 2002AbstractVarious types of cytogenetic and molecular cytogenetic approaches, including conventional banding, fluorescence in situ hybridization (FISH), fiber‐FISH, comparative genomic hybridization (CGH), matrix array CGH, chromosome microdissection, and microcell‐mediated chromosome transfer are summarized.
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New England Journal of Medicine, 1984
For many years it has been recognized that patients who apparently have the same type of leukemia have different prognoses and different responses to treatment.
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For many years it has been recognized that patients who apparently have the same type of leukemia have different prognoses and different responses to treatment.
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Current Opinion in Oncology, 2000
Techniques based on fluorescence in situ hybridization (FISH) have bridged the gap between molecular genetics and conventional cytogenetics. Since its introduction in the late 1980s, advanced FISH-based methods have greatly enhanced the cytogenetic analysis of hematopoietic and solid tumors and are rapidly gaining ground in clinical cytogenetic ...
A S, Patel, A L, Hawkins, C A, Griffin
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Techniques based on fluorescence in situ hybridization (FISH) have bridged the gap between molecular genetics and conventional cytogenetics. Since its introduction in the late 1980s, advanced FISH-based methods have greatly enhanced the cytogenetic analysis of hematopoietic and solid tumors and are rapidly gaining ground in clinical cytogenetic ...
A S, Patel, A L, Hawkins, C A, Griffin
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Archives of Internal Medicine, 1960
The direct study of human chromosomes has only recently become of significance in medicine. This has been made possible by several important advances in cytological technique, leading to the unexpected discovery in 1956 by Tjio and Levan 1 that the human chromosome number was 46 and not 48.
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The direct study of human chromosomes has only recently become of significance in medicine. This has been made possible by several important advances in cytological technique, leading to the unexpected discovery in 1956 by Tjio and Levan 1 that the human chromosome number was 46 and not 48.
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Current Biology, 1992
Chromosome variants are well established as useful genetic markers and integral components both of the genetic structure of populations, and in speciation. The current explosion of molecular techniques is facilitating the localization of many DNA sequences, while a reassessment of the fitness of chromosome mutants challenges some classical views on ...
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Chromosome variants are well established as useful genetic markers and integral components both of the genetic structure of populations, and in speciation. The current explosion of molecular techniques is facilitating the localization of many DNA sequences, while a reassessment of the fitness of chromosome mutants challenges some classical views on ...
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Biology of the Cell, 1986
Classical cytogenetics is often tedious and many efforts have been made to develop other methods of chromosome analysis, among which flow karyotyping has recently emerged. Although less efficient than banding techniques to identify each chromosome, flow cytometry offers the opportunity of analyzing large quantities of chromosomes at a very high rate ...
A, Bernheim, R, Miglierina
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Classical cytogenetics is often tedious and many efforts have been made to develop other methods of chromosome analysis, among which flow karyotyping has recently emerged. Although less efficient than banding techniques to identify each chromosome, flow cytometry offers the opportunity of analyzing large quantities of chromosomes at a very high rate ...
A, Bernheim, R, Miglierina
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