Results 81 to 90 of about 129,688 (299)

Prenatal screening and diagnostic strategies for fetal genetic abnormalities: Comparison of international clinical guidelines

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract This study compares recommendations from international clinical guidelines regarding prenatal screening and diagnostic testing for fetal genetic abnormalities, including the role of non‐invasive prenatal testing (NIPT), invasive diagnostic procedures, and advanced genomic technologies.
Geovanna Saboia Veras, João Renato Bennini   +1 more
wiley   +1 more source

Cytogenetic Nomenclature and Reporting

, 2016
A standardized nomenclature is critical for the accurate and consistent description of genomic changes as identified by karyotyping, fluorescence in situ hybridization and microarray.
Hastings, R.J., Katrina Rack, Stevens-Kroef, M.J., Annet Simons, Rosalind J. Hastings, Rack, K., Simons, A., Marian Stevens-Kroef   +7 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

A De Novo Deletion of Chromosome 18p with Persistent Limb Tremor and Difficulty Speaking

Caspian Journal of Neurological Sciences, 2019
Background: The common causes of 18p deletion syndrome are spontaneous errors in the chromosomal structure in the early stages of human embryonic development.
Aghil Esmaeili-Bandboni, Arash Davoudi, Forozan Milani, Sara Afzali, Alireza Sharafshah, Fereshteh Fallahabadi, Parvaneh Keshavarz   +6 more
doaj  

Cryptic terminal chromosome rearrangements in colorectal carcinoma cell lines detected by subtelomeric FISH analysis.

, 2006
Epithelial tumour karyotypes are often difficult to study by standard cytogenetic methods because of poor chromosome preparation quality and the high complexity of their genomic rearrangements.
Stewénius, Ylva, Wiegant, J, Tanke, H J, Stewénius, Ylva,, Lund University., Gisselsson Nord, David,, Gisselsson Nord, David   +6 more
core   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

Prognostic Significance of Peripheral Blood Neutrophil‐To‐Lymphocyte Ratio (NLR), Monocyte‐To‐Lymphocyte Ratio (MLR), and Platelet‐To‐Lymphocyte Ratio (PLR) in Patients With Multiple Myeloma: A Retrospective Cohort Study

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the prognostic significance of systemic inflammatory markers in Multiple Myeloma (MM). The left panel depicts the immunosuppressive tumor microenvironment, where abundant neutrophils and M2 macrophages promote MM cell survival while lymphocytes are depleted.
Lihong Zhang, Bing Ma, Jingyu Zhang
wiley   +1 more source

Langerhans Cell Histiocytosis Followed by Hodgkin Lymphoma: A Case Report

Iranian Journal of Medical Sciences, 2015
Langerhans cell histiocytosis (LCH) is a rare neoplasm defined as the proliferation of bone marrow langerhans cells, which is a kind of dendritic cells.
Akbar Safaei, Mandana Bagheri, Jahanbanoo Shahryari, Sadat Noori, Elmira Esmailzade   +4 more
doaj  

Cytogenetics of Pennisetum purpureum Schumack x Pennisetum glaucum L. hybrids and their parents Citogenética de híbridos entre Pennisetum purpureum Schumack E Pennisetum glaucum L. e seus genitores

Ciência e Agrotecnologia, 2003
Cytogenetic studies were carried out on five accesses of interspecific hybrids of Pennisetum purpureum and Pennisetum glaucum and their parentals, which are part of the Forage Germplasm Bank of the "Centro Nacional de Pesquisa de Gado de Leite" of ...
Sandro Barbosa, Lisete Chamma Davide, Antônio Vander Pereira   +2 more
doaj   +1 more source

Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat

Journal of Clinical Laboratory Analysis, EarlyView.
Distal 1q43q44 deletions lead to a consistent neurodevelopmental phenotype characterized by microcephaly, corpus callosum abnormalities, and developmental delay. Despite differences in genomic architecture, overlapping deletions affecting dosage‐sensitive genes such as AKT3, HNRNPU, and ZBTB18 define the core phenotype.
Ma. Guadalupe Domínguez‐Quezada, Horacio Rivera, Luis E. Figuera, Patricio Barros‐Núñez, José Luis Castrillo, Carlos Córdova‐Fletes, Thania Alejandra Aguayo‐Orozco   +6 more
wiley   +1 more source