Cytological features of penaut genome [PDF]
The genus Arachis is composed of 82 species (Krapovickas and Gregory 1994; Valls and Simpson 2005; Valls et al 2013; Santana and Valls 2015) mainly distributed within a large region of South America, which extends from the eastern foothills of the Andes ...
Chalup, Laura María Isabel+6 more
core +1 more source
Alternative statistical methods for cytogenetic radiation biological dosimetry [PDF]
The paper presents alternative statistical methods for biological dosimetry, such as the Bayesian and Monte Carlo method. The classical Gaussian and robust Bayesian fit algorithms for the linear, linear-quadratic as well as saturated and critical calibration curves are described. The Bayesian model selection algorithm for those curves is also presented.
arxiv
A novel three-colour fluorescence in situ hybridization approach for the detection of t(7;12)(q36;p13) in acute myeloid leukaemia reveals new cryptic three way translocation t(7;12;16) [PDF]
© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).The t(7;12)(q36;p13 ...
Abdulbasit Naiel+14 more
core +2 more sources
TP53 ‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53 mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah+2 more
wiley +1 more source
The lack of clear morphological markers of cotton chromosomes contributed to the development of an unconventional method for marking chromosomes using translocations. Today, tester translocation cotton lines represent the most complete set of cytological
M. F. Sanamyan, Sh. U. Bobokhujayev
doaj +1 more source
ABSTRACT With the recent publication of new classification systems of hematopoietic neoplasms, understanding how recognition of disease entities has occurred over time and the subsequent development of formal disease classifications is of importance. This review focuses on the early recognition of myeloid disorders, especially chronic myeloid disorders,
Daniel A. Arber, Attilio Orazi
wiley +1 more source
Use of copula to model within-study association in bivariate meta-analysis of binomial data at the aggregate level a Bayesian approach and application to surrogate endpoint evaluation [PDF]
Bivariate meta-analysis provides a useful framework for combining information across related studies and has been utilised to combine evidence from clinical studies to evaluate treatment efficacy on two outcomes. It has also been used to investigate surrogacy patterns between treatment effects on the surrogate endpoint and the final outcome.
arxiv
A Novel Application of Image-to-Image Translation: Chromosome Straightening Framework by Learning from a Single Image [PDF]
In medical imaging, chromosome straightening plays a significant role in the pathological study of chromosomes and in the development of cytogenetic maps. Whereas different approaches exist for the straightening task, typically geometric algorithms are used whose outputs are characterized by jagged edges or fragments with discontinued banding patterns.
arxiv
The micronucleus assay in radiation accidents [PDF]
The cytokinesis-block micronucleus assay in peripheral blood lymphocytes is a standardised and validated technique for biodosimetry. Automated scoring of micronuclei allows large scale applications as in population triage in case of radiation accidents ...
Thierens, Hubert, Vral, Anne
core +1 more source
Multicolor chromosome bar codes [PDF]
Chromosome bar codes are multicolor banding patterns produced by fluorescence in situ hybridization (FISH) with differentially labeled and pooled sub-regional DNA probes.
Müller, Stefan, Wienberg, Johannes
core +1 more source