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Cytogenetic analysis of human blastocysts
Prenatal Diagnosis, 2002AbstractThe human blastocyst is key to understanding the aetiology of constitutional chromosome abnormalities in our species.ObjectivesTo investigate the range and incidence of chromosome abnormalities in a large series of human blastocysts, using classic cytogenetic techniques.MethodsUsing thymidine, cell division is synchronized in spare five‐to ...
Clouston HJ +4 more
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Cytogenetic Analysis in Leukemia
CRC Critical Reviews in Clinical Laboratory Sciences, 1975(1975). Cytogenetic Analysis in Leukemia. CRC Critical Reviews in Clinical Laboratory Sciences: Vol. 6, No. 3, pp. 157-200.
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Cytogenetic analysis of a leiomyosarcoma of the kidney
Cancer Genetics and Cytogenetics, 1994Nonepithelial malignant renal tumors are very rare, comprising approximately 2-3% of all malignant renal tumors. We were able to culture and subsequently karyotype a leiomyosarcoma (LMS) of the kidney that showed the following representative karyotype: 84,XY,add(X)(q25),-Y,add(1)(p11),dic(1;20) (p34;q13.3),-5,-6,dup(6)(q24),i(7)(p10),add(8)(p11),-9,-11,
van den Berg, Eva +5 more
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Cytogenetic analysis of a uterine lipoleiomyoma
Cancer Genetics and Cytogenetics, 1992We cytogenetically analyzed a uterine lipoleiomyoma. A primary chromosomal abnormality, t(12;14), was found in all 62 cells studied. A secondary change involving chromosomes 1 and 5 was detected in 15 of 62 cells. These findings suggest that lipoleiomyomas share the same chromosomal abnormalities found in common leiomyomas.
J, Hu, U, Surti, H, Tobon
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Cytogenetic analysis in human neurinomas
Cancer Genetics and Cytogenetics, 1987In a recent report, Seizinger et al. [1], using a molecular genetic approach, have shown that acoustic neuroma is associated with loss of genes on chromosome #22, suggesting a mechanism of tumorigenesis similar to that found in embryonal tumors [2-6].
J A, Rey +4 more
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Cytogenetic analysis of malignant mesothelioma
Cancer Genetics and Cytogenetics, 1990Cytogenetic analyses of 40 confirmed malignant mesotheliomas (MMs) are reported. Pleural effusion cells were studied in 90% of the cases by direct method or after culture or both. Biopsy and ascites fluid were also analyzed in some patients. A normal karyotype was found in nine cases, and complex karyotypic abnormalities were observed in 30 cases.
Hagemeijer, A. +6 more
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Interphase cytogenetic analysis of gliomas
Clinical Neurology and Neurosurgery, 1992Interphase cytogenetics is the application of nonradioactive in situ hybridization with chromosome-specific DNA probes to interphase nuclei. The possibilities and limitations of this new technique for the study of chromosomal aberrations in gliomas are discussed.
E P, Arnoldus +3 more
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Cytogenetic analysis of choroidal melanoma
Archivos de la Sociedad Española de Oftalmología (English Edition), 2014To investigate the presence of known cytogenetic alterations of choroidal melanoma in a series of patients diagnosed and treated in our Ocular Oncology Service. A review of the present literature on this topic is also presented.Microsatellite analysis (MSA) studies on loss of heterozygosity (LOH) of chromosome 3, as well as multiplex ligation prove ...
A, Filloy +5 more
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Cytogenetic analysis of dedifferentiated chondrosarcoma
Cancer Genetics and Cytogenetics, 1996Cytogenetic analysis of a dedifferentiated chondrosarcoma with a fibrosarcomatous component revealed the following chromosomal complement: 47,XX,i(1)(q10), add(6)(q13),+7,+8,t(10;12) (p11.2;q11.2),+14,-15,-17, add(19)(q13,4). Chromosome studies of dedifferentiated chondrosarcoma are sparse.
S J, Swarts +3 more
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Classical and Molecular Cytogenetic Analysis
2012Cytogenetic analysis is performed on cell cultures for several reasons, notably, to perform identity checks by verifying species of origin or the retention of key chromosome rearrangements in cell lines described previously. De novo chromosome analysis is usually performed when characterizing cancer cell lines for the presence of neoplastic ...
Roderick A F, MacLeod, Hans G, Drexler
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