Results 121 to 130 of about 74,783 (169)
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Cytogenetic analysis of a congenital fibrosarcoma
Cancer Genetics and Cytogenetics, 1991Congenital (infantile) fibrosarcoma is a rare soft tissue sarcoma occurring in children aged less than 5 years. We performed cytogenetic analysis on such a tumor, which had an abnormal karyotype: 48,XY, +11, +20. Three other reports of karyotypes in congenital fibrosarcoma describe similar cytogenetic changes, and a specific pattern of trisomies that ...
Adam +9 more
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Overview of Cytogenetic Chromosome Analysis
Current Protocols in Cell Biology, 2004AbstractThis unit provides a brief overview of cytogenetic analysis of interphase ansd metaphase chromosomes. It includes a description of the methods provided in the units that follow.
Jane, Bayani, Jeremy A, Squire
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Cytogenetic Analysis and Reporting
2011Use of appropriate methods to produce analysable metaphase spreads and high-quality fluorescence in situ hybridization (FISH) and array results is critical to successful cytogenetic analysis of haematological malignancies, but the analysis and reporting of the findings of these tests are equally important as it is the final report that clinicians rely ...
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Cytogenetic analysis of dermatofibrosarcoma protuberans
Cancer Genetics and Cytogenetics, 1990A case of dermatofibrosarcoma protuberans that occurred in an old burn scar over the anterior chest wall of a 46-year-old man is reported. Cytogenetic analysis of the tumor cells showed the presence of two abnormal clones: 47,XY, +8 and 48,XY, +8, +r.
J A, Bridge, J R, Neff, A A, Sandberg
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Cytogenetic analysis in congenital hypothyroidism
Journal of Endocrinological Investigation, 1990In order to evaluate the possible role of genetic factors in the pathogenesis of congenital hypothyroidism (CH), we investigated the occurrence of chromosome aberrations in a consecutive series of 47 patients with CH and 208 matched healthy controls. No abnormal karyotype was found in CH patients.
F, Uccellatore +6 more
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Cytogenetic Analysis of Cell Lines
2004Cytogenetic analysis forms an essential part of characterizing and identifying cell lines, in particular those established from tumors. In addition, karyotypic analysis can be used to distinguish individual subclones and to monitor stability. This chapter describes basic cytogenetic procedures suited to cells in continuous culture.
Roderick A F, MacLeod, Hans G, Drexler
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Cytogenetic Analysis of Sinonasal Carcinomas
Otolaryngology–Head and Neck Surgery, 2006BACKGROUNDSinonasal carcinomas, including nonkeratinizing (NK) squamous cell carcinoma (SCC) and sinonasal undifferentiated carcinoma (SNUC), are uncommon malignant neoplasms arising from the Schneiderian respiratory epithelium of the nasal cavity and paranasal sinuses.
Ziv, Gil +6 more
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1995
Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Cytogenetic Analysis of Tumor Clonality
2011All or almost all neoplasias subjected to systematic cytogenetic scrutiny have been found to harbor acquired chromosomal aberrations. The paradigm stemming from the study of hematopoietic malignancies and sarcomas is that cancers are of monoclonal origin (i.e., they have developed from a single transformed somatic progenitor) because all the neoplastic
Manuel R, Teixeira, Sverre, Heim
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Cytogenetic analysis of renal angiomyolipoma
Genes, Chromosomes and Cancer, 1992AbstractChromosome analysis of a benign, unilateral, renal angiomyolipoma revealed the karyotype 44,XX, –8, –12, –14, –21, + der (8q14q), + der(12)(12pter → 12q14‐15:: 12q24 → 12q14–15::21q21 → 21 qter). This indicates that structural changes of 12q13‐15, which are so frequently observed in the common malignant and benign lipogenic tumors, may also ...
M, Debiec-Rychter +2 more
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