Results 161 to 170 of about 22,374,088 (435)

Efeitos adversos e resposta citogenética em pacientes com leucemia mieloide crônica tratados com imatinibe Adverse events and cytogenetc response in patients with chronic myeloid leukemia treated with imatinib

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2010
A leucemia mieloide crônica (LMC) é uma doença mieloproliferativa clonal caracterizada citogeneticamente pelo cromossomo Philadelphia. Dentre as opções terapêuticas estão a hidroxiureia, o interferon-a, o transplante alogeneico de células-tronco ...
Tatiana F. Alvarenga   +6 more
doaj  

Improved identification of clinically relevant Acute Leukemia subtypes using standardized EuroFlow panels versus non‐standardized approach

open access: yesCytometry Part B: Clinical Cytometry, Volume 108, Issue 2, Page 116-127, March 2025.
Abstract Rare acute leukemia (AL) components or subtypes such as blastic plasmacytoid dendritic cell neoplasm (BPDCN) or early T‐cell precursor acute Lymphoblastic Leukemia (ETP‐ALL) can be difficult to detect by routine flow cytometry due to their immunophenotypes overlapping with other poorly differentiated AL. We hypothesized that using standardized
Rafik Terra   +9 more
wiley   +1 more source

Leucemia promielocítica aguda: caracterização de alterações cromossômicas por citogenética tradicional e molecular (FISH) Acute promyelocytic leukemia: characterization of chromosome abnormalities by classical cytogenetics and FISH

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2005
A leucemia promielocítica aguda (LPA) corresponde a 10% -15% das leucemias mielóides agudas (LMA). Este tipo de leucemia (LMA-M3 de acordo com a classificação FAB) está associado, em cerca de 90% dos casos, à translocação t(15;17)(q22;q21), que resulta ...
Michele R. Sagrillo   +9 more
doaj   +1 more source

ClearLLab 10C reagents panel can be applied to analyze paucicellular samples by flow cytometry

open access: yesCytometry Part B: Clinical Cytometry, Volume 108, Issue 2, Page 128-136, March 2025.
Abstract The FDA‐approved ClearLLab 10C Reagents Panel (Beckman Coulter) simplified the diagnosis of leukemias and lymphomas by flow cytometry. However, the requirement of using 3 × 106 cells/mL cannot be met for paucicellular samples. Therefore, we tested whether this 10‐color panel can be reliably employed to analyze specimens with low cell ...
Małgorzata Kajstura   +2 more
wiley   +1 more source

CYTOGENETIC ANALYSIS OF PATIENTS WITH AMBIGUOUS GENITALIA

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To determine the magnitude and classification of cases of ambiguous genitalia presenting to our setup. Study Design: Cross-sectional study.
Sara Ali Zaidi   +5 more
doaj  

Modeling Intratumor Gene Copy Number Heterogeneity using Fluorescence in Situ Hybridization data [PDF]

open access: yesarXiv, 2013
Tumorigenesis is an evolutionary process which involves a significant number of genomic rearrangements typically coupled with changes in the gene copy number profiles of numerous cells. Fluorescence in situ hybridization (FISH) is a cytogenetic technique which allows counting copy numbers of genes in single cells.
arxiv  

Focus on the Holdrinet index: Toward blast quantification by flow cytometry

open access: yesCytometry Part B: Clinical Cytometry, Volume 108, Issue 2, Page 137-145, March 2025.
Abstract Blast quantification in the bone marrow (BM) is crucial for evaluating myeloid neoplasms, with cytomorphology being the only recognized analysis. The CD34 myeloid cell (CD34M) count by flow cytometry is promising but impaired by BM hemodilution.
Edouard Bonneville   +5 more
wiley   +1 more source

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