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Cytogenetic Analysis of Sinonasal Carcinomas
Otolaryngology–Head and Neck Surgery, 2006BACKGROUNDSinonasal carcinomas, including nonkeratinizing (NK) squamous cell carcinoma (SCC) and sinonasal undifferentiated carcinoma (SNUC), are uncommon malignant neoplasms arising from the Schneiderian respiratory epithelium of the nasal cavity and paranasal sinuses.
Ziv, Gil +6 more
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Cytogenetic Analysis of Tumor Clonality
2011All or almost all neoplasias subjected to systematic cytogenetic scrutiny have been found to harbor acquired chromosomal aberrations. The paradigm stemming from the study of hematopoietic malignancies and sarcomas is that cancers are of monoclonal origin (i.e., they have developed from a single transformed somatic progenitor) because all the neoplastic
Manuel R, Teixeira, Sverre, Heim
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Cytogenetic analysis of renal angiomyolipoma
Genes, Chromosomes and Cancer, 1992AbstractChromosome analysis of a benign, unilateral, renal angiomyolipoma revealed the karyotype 44,XX, –8, –12, –14, –21, + der (8q14q), + der(12)(12pter → 12q14‐15:: 12q24 → 12q14–15::21q21 → 21 qter). This indicates that structural changes of 12q13‐15, which are so frequently observed in the common malignant and benign lipogenic tumors, may also ...
M, Debiec-Rychter +2 more
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1995
Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Cytogenetic analysis of unfertilized human oocytes
Human Reproduction, 1991Cytogenetic studies were carried out on 180 oocytes that appeared unfertilized after in-vitro fertilization. The majority of the 135 that were informative had grossly haploid second meiotic metaphases, two were grossly diploid, and five had a variety of different abnormalities.
Angell, R. R. +4 more
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Cytogenetic analysis in melanoma and nevi
1991We have presented data from the cytogenetic analysis of melanocytes derived from four dysplastic nevi and 14 melanomas. We have confirmed previous results from melanomas, including the loss of chromosome 6q and duplication of 1q and 7p. We did not observe an excess of rearrangements involving chromosomes 2 and 3, but we found frequent deletion of ...
J M, Cowan, U, Francke
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PRENATAL CYTOGENETIC ANALYSIS OF THE FETUS
Obstetrics and Gynecology Clinics of North America, 1993A number of different cell sources can be used for prenatal cytogenetic analysis, the most common being chorionic villi and amniotic fluid. Analysis can be done at any time between 9 weeks' gestation and term. Depending on the cell source and type of analysis required, the laboratory will take anywhere from 24 hours to 2 weeks to complete the study.
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Cytogenetic analysis by chromosome painting
Cytometry, 1994AbstractChromosome painting is a term used to describe the direct visualisation using in situ hybridisation of specific chromosomes in metaphase spreads and in interphase nuclei. Chromosome painting, coupled with fluorescence in situ hybridisation (FISH), is now used routinely to enhance the identification of chromosomal rearrangements, the assignment ...
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The Interpretation and Analysis of Cytogenetic Data
2011Chromosome aberration analysis has been the basis of one of core tests in genetic toxicology since guidelines were first established (DHSS (1981) Guidelines for the Testing of Chemicals for Mutagenicity. Prepared by the Committee on Mutagenicity of Chemcials in Food, Consumer Products, and the Environment, Department of Health and Social Security ...
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Rinsho byori. The Japanese journal of clinical pathology, 2001
We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our ...
S, Miyanishi, A, Okumura
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We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our ...
S, Miyanishi, A, Okumura
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