Toxicological Investigations of Aristolochia longa Root Extracts
Aristolochia longa L. (Aristolochiaceae) is an herbaceous plant recognized in alternative medicine for its many therapeutic virtues. The aim of this study was to determine the pharmacotoxicological effects of this plant in order to ensure safe clinical ...
Nasreddine El Omari +9 more
doaj +1 more source
Cytogenetic analysis of meningiomas [PDF]
Cytogenetic analysis of 4 cases of meningiomas from 3 male and 1 female patients is reported. One of male patients suffered from neurofibromatosis type 2. Histologically, the meningiomas were meningotheliomatous (1), transitional (2), and psammomatous (1). Chromosomal abnormalities were found in all cases with a karyotype 45,XY,-22, 45,XY,-16, 45,XX,-2,
J H, Cho +5 more
openaire +2 more sources
The long-term storage of unutilized pesticides raised new problems of long-term environmental contamination. The study presents the results of surveying 151 individuals in 7 villages living close to pesticide-contaminated localities. All individuals have
Aleksandr Garshin +11 more
doaj +1 more source
Cytogenetic Analysis of Telomere Dysfunction [PDF]
Dysfunctional telomeres arising either through natural attrition due to telomerase deficiency or by the removal of telomere-binding proteins are recognized as double-stranded breaks (DSBs). Repair of DSBs is crucial for the maintenance of genome stability.
Rekha, Rai +2 more
openaire +4 more sources
Clinical genetic description and analysis of the case of chromosomal mosaicism mos47,XY,+8/46,XY
The article describes a clinical case of chromosomal mosaicism in a boy, 4 months and 3 weeks old. Cytogenetic analysis of peripheral blood lymphocytes of the child made it possible to establish the karyotype mos47,XY,+8/46,XY with an approximately equal
s L. Nersesyan +2 more
doaj +1 more source
Molecular markers and cytogenetics of Eleven O’Clock Portulaca umbraticola: a non-conventional edible ornamental crop [PDF]
Portulaca umbraticola, commonly known as “Eleven o'clock”, is a popular ornamental plant in Brazil, but its potential as a non-conventional food source remains underexplored.
J. S. Souza +6 more
doaj +1 more source
Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas +5 more
core +1 more source
Multiplex ligation-dependent probe amplification – a short overview
Multiplex Ligation-dependent Probe Amplification is a technique proposed for the detection of deletions or duplications that may lead to copy number variations in genomic DNA, mainly due to its higher resolution, and shorter overall diagnosis time, when ...
Moldovan Valeriu, Moldovan Elena
doaj +1 more source
Assessment of Bone Marrow Biopsy and Cytogenetic Findings in Patients with Multiple Myeloma
Objective: Multiple myeloma (MM) is a malignant condition characterized by the accumulation of malignant plasma cells. Although MM remains incurable, the survival of MM patients has improved considerably due to the application of autologous stem cell ...
Ahmet Seyhanlı +8 more
doaj +1 more source
Clonal karyotype evolution involving ring chromosome 1 with myelodysplastic syndrome subtype RAEB-t progressing into acute leukemia [PDF]
s Karyotypic evolution is a well-known phenomenon in patients with malignant hernatological disorders during disease progression. We describe a 50-year-old male patient who had originally presented with pancytopenia in October 1992.
Bennett JM +46 more
core +1 more source

