Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1986 This report describes the use of fluorescence in situ hybridization for chromosome classification and detection of chromosome aberrations. Biotin-labeled DNA was hybridized to target chromosomes and subsequently rendered fluorescent by successive ...
Daniel Pinkel, T. Straume, Joe W. Gray
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Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers. [PDF]
N Engl J Med, 2021 BACKGROUND Genomic analysis is essential for risk stratification in patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Whole-genome sequencing is a potential replacement for conventional cytogenetic and sequencing approaches ...
Duncavage EJ +26 more
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Unravelling the Impact of an Additional Sex Chromosome in an Adult Female
Journal of Human Reproductive Sciences, 2023 Women with Triple X syndrome (TXS) appear to be at increased risk for decreased ovarian reserve; however, available data are limited. We present an asyndromic adult female with features of recurrent pregnancy loss and decreased ovarian reserve detected ...
Sigin George +3 more
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Cytoembryological evaluation, meiotic behavior and pollen viability of Paspalum notatum tetraploidized plants [PDF]
Crop Breeding and Applied Biotechnology, 2016 This study evaluated the mode of reproduction, the meiotic behavior and the pollen viability of three tetraploid plants (2n=4x=40) originated from somatic chromosome duplication of Paspalum notatum plants. The plant WKS 3 changed the mode of reproduction
Karine Cristina Krycki +2 more
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Molecular Cytogenetic Study in Patients with Acute Lymphoblastic Leukemia (ALL) in Erbil Province
Zanco Journal of Pure and Applied Sciences, 2021 Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and is also important in older adults. Chromosome number or structure abnormalities are seen in approximately 90% of children and 70% of adult patients with ALL. The
Heveen Omar Hassan, Nadhum Jalal Esmael
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A Bone Marrow Study; Report of Chromosomal Variations in Hematologic Malignancies Including Acute Myeloid Leukemia, Acute Lymphoid Leukemia, and Myelodisplastic Syndrome (Northeast Iran) [PDF]
Middle East Journal of Cancer, 2021 Background: Chromosomal aberrations which occur in different hematologic malignancies are believed to be highly applicable for identifying the prognosis and treatment protocols.
Sepideh Shakeri +3 more
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A clinical case of inverted duplication with terminal deletion of the short arm of chromosome 5
Alʹmanah Kliničeskoj Mediciny, 2020 The 5p inverted duplication deletion syndrome, also known as inv dup del 5p, is a rare genetic disorder with a prevalence of below 1:1 000 000, whose underlying abnormality lies in a segmental trisomy and simultaneous segmental monosomy of the short arm ...
O. A. Solovova +4 more
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Assessment of Bone Marrow Biopsy and Cytogenetic Findings in Patients with Multiple Myeloma
Turkish Journal of Hematology, 2022 Objective: Multiple myeloma (MM) is a malignant condition characterized by the accumulation of malignant plasma cells. Although MM remains incurable, the survival of MM patients has improved considerably due to the application of autologous stem cell ...
Ahmet Seyhanlı +8 more
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Assessment of Molecular Cytogenetic Methods for the Detection of Chromosomal Abnormalities [PDF]
, 2006 Some marker chromosomes and chromosome rearrangements are difficult to identify using G-bands by Giemsa staining after trypsin treatment (G-banding) alone.
Maruyama, Hidehiko +5 more
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Taiwanese Journal of Obstetrics & Gynecology, 2016 Objective: Pallister–Killian syndrome (PKS) is a rare, sporadic genetic disorder caused by mosaic tetrasomy of the short arm of chromosome 12 (12p).
Francesco Libotte +9 more
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