Results 191 to 200 of about 22,374,088 (435)

The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia

Glia, EarlyView.
ABSTRACT The SORL1 gene encodes the sortilin‐related receptor protein SORLA, a sorting receptor that regulates endo‐lysosomal trafficking of various substrates. Loss of function variants in SORL1 are causative for Alzheimer's disease (AD) and decreased expression of SORLA has been repeatedly observed in human AD brains. SORL1 is highly expressed in the
Swati Mishra, Nader Morshed, Sonia Beant Sidhu, Chizuru Kinoshita, Beth Stevens, Suman Jayadev, Jessica E. Young   +6 more
wiley   +1 more source

Expanding the Chromosomal Evolution Understanding of Lygaeioid True Bugs (Lygaeoidea, Pentatomomorpha, Heteroptera) by Classical and Molecular Cytogenetic Analysis. [PDF]

Genes (Basel), 2023
Golub NV, Maryańska-Nadachowska A, Anokhin BA, Kuznetsova VG.   +3 more
europepmc   +1 more source

Chromosomal abnormalities in products of conception of first-trimester miscarriages detected by conventional cytogenetic analysis: a review of 1000 cases

Journal of Assisted Reproduction and Genetics, 2018
L. Pylyp, Lyudmyla O Spynenko, Nataliya V Verhoglyad, Anna O Mishenko, D. Mykytenko, V. Zukin   +5 more
semanticscholar   +1 more source

Research status of fetal hydrocephalus from 2003 to 2022 based on bibliometric analysis

Ibrain, EarlyView.
In this study, we extracted 613 articles related to hydrocephalus from the Web of Science Core Collection (WOSCC) database published from January 01, 2003 to December 31, 2022, and 613 articles were obtained after weight reduction using CiteSpace. CiteSpace and VOSviewer software were used to extract and visualize the elements of the article, including
Qian Li, Zheyu Song, Chenyang Zhai, Sajid Hussain, Wenxue Zhao, Shunwu Xiao   +5 more
wiley   +1 more source

Molecular and Cytogenetic Analysis of rDNA Evolution in Crepis Sensu Lato. [PDF]

Int J Mol Sci, 2022
Senderowicz M, Nowak T, Weiss-Schneeweiss H, Papp L, Kolano B.   +4 more
europepmc   +1 more source

Immunophenotypic and cytogenetic analysis of Molt-3 and Molt-4: human T- lymphoid cell lines with rearrangement of chromosome 7 [PDF]

, 1988
JM Greenberg, Rogelio González‐Sarmiento, DC Arthur, CW Wilkowski, BJ Streifel, JH Kersey   +5 more
openalex   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Cytogenetic Analysis of the Members of the Snake Genera Cylindrophis, Eryx, Python, and Tropidophis. [PDF]

Genes (Basel), 2022
Charvát T, Augstenová B, Frynta D, Kratochvíl L, Rovatsos M.   +4 more
europepmc   +1 more source

DNA analysis using long-term preserved fixed cytogenetic preparations [PDF]

, 1988
H Nishigaki, Tsukasa Okuda, Shigeo Horiike, Shoíchiro Tsuda, Masafumi Taniwaki, S Misawa, Johji Inazawa, Tatsuo Abe   +7 more
openalex   +1 more source

Epigenetic reprogramming in multiple myeloma—Challenges and opportunities

International Journal of Cancer, EarlyView.
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar, Lev M. Kats, Emily Gruber   +2 more
wiley   +1 more source