Results 271 to 280 of about 148,275 (313)
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1995
Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Cytogenetic Analysis of Cell Lines
2004Cytogenetic analysis forms an essential part of characterizing and identifying cell lines, in particular those established from tumors. In addition, karyotypic analysis can be used to distinguish individual subclones and to monitor stability. This chapter describes basic cytogenetic procedures suited to cells in continuous culture.
Roderick A F, MacLeod, Hans G, Drexler
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Rinsho byori. The Japanese journal of clinical pathology, 2001
We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our ...
S, Miyanishi, A, Okumura
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We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our ...
S, Miyanishi, A, Okumura
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Cytogenetic analysis by chromosome painting
Cytometry, 1994AbstractChromosome painting is a term used to describe the direct visualisation using in situ hybridisation of specific chromosomes in metaphase spreads and in interphase nuclei. Chromosome painting, coupled with fluorescence in situ hybridisation (FISH), is now used routinely to enhance the identification of chromosomal rearrangements, the assignment ...
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Cytogenetic analysis of a uterine lipoleiomyoma
Cancer Genetics and Cytogenetics, 1992We cytogenetically analyzed a uterine lipoleiomyoma. A primary chromosomal abnormality, t(12;14), was found in all 62 cells studied. A secondary change involving chromosomes 1 and 5 was detected in 15 of 62 cells. These findings suggest that lipoleiomyomas share the same chromosomal abnormalities found in common leiomyomas.
J, Hu, U, Surti, H, Tobon
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Cytogenetic analysis in nine leukaemic cats
Journal of Comparative Pathology, 1989Eight of nine leukaemic cats had chromosomal abnormalities. The major differences between the healthy, FeLV-negative control cats and the leukaemic cats were the increased number of hyperdiploid cells and the presence of double minute or morphologically abnormal chromosomes in the leukaemic cats.
C B, Grindem, L C, Buoen
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Cytogenetic Analysis of Cancer Cell Lines
2011Cancer genes are often deregulated by genomic rearrangements. Accordingly, analysis of the participant chromosomes responsible now occupies a key role in characterizing and identifying cancer cell lines. Cytogenetics may also be used to study the nature and extent of chromosome breakage induced by radiation or chemicals ("clastogenesis"), to ...
Roderick A F, Macleod +2 more
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Techniques for Cytogenetic Analysis
1978This chapter is essentially a compilation of techniques for the preparation of mitotic and meiotic chromosomes from a variety of starting materials. Section I deals with what I consider to be the ideal technique for karyotypic analysis: the preparation of mitotic chromosomes from cultured cells of fetal origin.
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Human Cytogenetics: constitutional analysis
2001Abstract Human Cytogenetics: Constitutional Analysis covers all basic aspects of human cytogenetic study other than malignancies and abnormalities. They are covered in a separate volume. Since the publication of the 2nd edition in 1992, there have been major advances in technology and the emphasis of this new edition is on the ...
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