Results 21 to 30 of about 154,528 (340)

A Rare Cause of Hypotonia: 49,XXXXX (Pentasomy X)

The Journal of Pediatric Academy, 2023
Pentasomy X syndrome is a very rare sex chromosome numerical anomaly of unknown frequency. The karyotype consists of 49,XXXXX. Musculoskeletal, craniofacial, cardiac, and kidney anomalies accompany psychomotor developmental delays. This report describes,
Kübra Aydoğan, Selcan Öztürk, Munis Dündar, Hakan Gümüş, Çetin Saatçi, Hüseyin Per   +5 more
doaj   +1 more source

Excellent outcomes of 2G-TKI therapy after imatinib failure in chronic phase CML patients [PDF]

, 2018
open25noSecond-generation tyrosine kinase inhibitors (2G-TKIs) dasatinib and nilotinib produced historical rates of about 50% complete cytogenetic response (CCyR) and about 40% major molecular response (MMR) in chronic myeloid leukaemia (CML) patients ...

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Mixoploidia em híbridos de capim-elefante x milheto tratados com agentes antimitóticos Mixoploidy in napiergrass x pearl millet hybrids treated with antimitotic agents

Pesquisa Agropecuária Brasileira, 2006
O objetivo deste trabalho foi avaliar métodos de duplicação cromossômica, com uso de agentes antimitóticos e diversos materiais botânicos como explantes dos híbridos entre capim-elefante (Pennisetum purpureum Schum.) e milheto (Pennisetum glaucum (L.) R.
Juscélio Clemente de Abreu, Lisete Chamma Davide, Antônio Vander Pereira, Sandro Barbosa   +3 more
doaj   +1 more source

Biomarkers of leukemia risk: benzene as a model. [PDF]

, 1998
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
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Near tetrapoloid karyotype with translocation t(11;14) in a Moroccan patient with amyloid light-chain amyloidosis and multiple myeloma

Leukemia Research Reports, 2020
Cytogenetic and iFISH plays a major part in the diagnosis of the MM and have an important prognostic significance.10–15% of patients with amyloidosis will also have multiple myeloma (MM).
Hasna Hamdaoui, Abdelhafid Natiq, Oumaima Benlarroubia, Thomas Liehr, Hind Dehbi, Latifa Loukhmas, Fatima Chegdani   +6 more
doaj   +1 more source

Toxicity of apple juice and its components in the model plant system [PDF]

Foods and Raw Materials, 2020
Introduction. In view of the ongoing research into the negative effects of fruit juice on human health, we aimed to study the subchronic toxicity of apple juice, a model mixture based on its components, and ethanol on biomass growth, cellular oxidative ...
Samoylov Artem V. , Suraeva Natal’ya M. , Zaytseva Mariya V. , Rachkova Vera P. , Kurbanova Madinat N. , Belozerov Georgy А.   +5 more
doaj   +1 more source

Clinical implications of discordant early molecular responses in CML patients treated with imatinib [PDF]

, 2019
A reduction in BCR-ABL1/ABL1IS transcript levels to <10% after 3 months or <1% after 6 months of tyrosine kinase inhibitor therapy are associated with superior clinical outcomes in chronic myeloid leukemia (CML) patients.
Accurso V., Antolino A., Di Raimondo F., Forte S., Impera S., Malato A., Mannina D., Manzella L., Martino B., Massimino M., Mineo G., Musolino C., Musso M., Pennisi M. S., Porretto F., Russo S., Siragusa S., Spitaleri A., Stagno F., Stella S., Tirro E., Vigneri P., Vitale S. R., Zammit V.   +23 more
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The polo-like kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia [PDF]

, 2013
CD56 is expressed in 15–20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis.
A Blair, A Cesano, A Vilas-Zornoza, AG Renner, Alessandro Rambaldi, Alessia Casolaro, Alice Pezzoni, B Löwenberg, B Valsasina, Barbara Valsasina, C McInnes, Clara Albanese, D Raspadori, E Di Bona, E Estey, E Radaelli, EM Lee, Enrico Pesenti, F Ravandi, FR Appelbaum, Francesco Bertolini, Francesco Marchesi, G Tsykunova, Gemma Texido, Gianni Cazzaniga, H Chang, I Beria, J Delgado, J Golay, J Suela, J Zuber, Josee Golay, JR Novontny, JW Rocco, K Strebhardt, M Bardini, Marco Losa, Martino Introna, MJ Walter, MR Baer, Nadia Amboldi, PA Greif, R Giavazzi, Rachele Alzani, Roberta Ceruti, S Gattenloehner, Sabrina Cribioli, Silvia Bungaro, T Berg, T Ikezoe, T Lapidot, TJ Ley, U Cucchi, Ursula Giussani, Veronica Patton, Z Li   +55 more
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Cytogenetic Analysis for Suspected Chromosomal Abnormalities; A Five Years Experience [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Chromosomal abnormalities are the results of alterations in the number or structure of chromosomes causing significant human morbidity and mortality.
Sunil Kumar Polipalli, Vijay Kumar Karra, Ankur Jindal, Madhavi Puppala, Pratiksha Singh, Kanchan Rawat, Seema Kapoor   +6 more
doaj   +1 more source

The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]

, 2010
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel, Thierens, Hubert, Vral, Anne   +2 more
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