Results 191 to 200 of about 2,225,287 (343)

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Erratum to: Longitudinal, natural history study reveals the disease burden of idiopathic multicentric Castleman disease

Haematologica, 2020
Mateo Sarmiento Bustamante, Sheila K. Pierson, Yue Ren, Adam Bagg, Joshua D. Brandstadter, Gordan Srkalovic, Natalie Mango, Daisy Alapat, Mary Jo Lechowicz, Hongzhe Li, Frits van Rhee, Megan S. Lim, David C. Fajgenbaum   +12 more
doaj   +1 more source

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, EarlyView.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

Abnormal gene and protein expression of inflammatory cytokines in the postmortem brain of schizophrenia patients

, 2017
Ghanshyam N. Pandey, Hooriyah S. Rizavi, Hui Zhang, Xinguo Ren   +3 more
openalex   +2 more sources

Effects of Different Ammonia Concentrations on Pulmonary Microbial Flora, Lung Tissue Mucosal Morphology, Inflammatory Cytokines, and Neurotransmitters of Broilers [PDF]

, 2022
Guangju Wang, Qingxiu Liu, Ying Zhou, Jinghai Feng, Minhong Zhang   +4 more
openalex   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

MicroRNA‑146a inhibits NF‑κB activation and pro‑inflammatory cytokine production by regulating IRAK1 expression in THP‑1 cells

, 2019
Chunlei Zhou, Lan Zhao, Kai Wang, Qianru Qi, Meng Wang, Lei Yang, Ping Sun, Hong Mu   +7 more
openalex   +2 more sources

Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone

Advanced Biology, EarlyView.
In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman, Bryan Guo, William W. Du, Burton Yang, Yu Sun, Lidan You   +5 more
wiley   +1 more source

S100 Proteins, Cytokines, and Chemokines as Tear Biomarkers in Children with Juvenile Idiopathic Arthritis-associated Uveitis

, 2020
Sheila T. Angeles‐Han, Virginia Miraldi Utz, Sherry Thornton, Grant S. Schulert, Jackeline Rodriguez‐Smith, Adam Kauffman, Alyssa Sproles, Najima Mwase, Theresa Hennard, Alexei A. Grom, Mekibib Altaye, Gary N. Holland   +11 more
openalex   +2 more sources

Longitudinal Analysis of Urinary Cytokines and Biomarkers in COVID-19 Patients with Subclinical Acute Kidney Injury [PDF]

, 2022
Gustavo Casas-Aparicio, Claudia Alvarado‐de la Barrera, David Escamilla-Illescas, Isabel León-Rodríguez, Perla M. Del Río Estrada, Mauricio González-Navarro, Natalia Calderón-Dávila, Rossana Olmedo-Ocampo, Manuel Castillejos‐López, Liliana Figueroa-Hernández, Amy Peralta-Prado, Yara Andrea Luna-Villalobos, Elvira Pitén-Isidro, Paola Fernández-Campos, Alejandro Juárez-Díaz, Karolina Piekarska, Santiago Ávila‐Ríos   +16 more
openalex   +1 more source