Results 171 to 180 of about 1,857,465 (364)
Frontiers in ImmunologyObjectiveThis article aims to investigate the changes of T helper 17 (Th17) cells, regulatory T (Treg) cells and their associated cytokines in patients with systemic lupus erythematosus (SLE).MethodsMultiple databases were investigated to identify ...
Jinge Huang +5 more
doaj +1 more source
Principles of interleukin (IL)-6-type cytokine signalling and its regulation.
Biochemical Journal, 2003 P. Heinrich +5 more
semanticscholar +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Modulation of cytokine production by cyclic adenosine monophosphate analogs in human leukocytes
, 2010 Cyclic adenosine monophosphate (cAMP) is a well-known second messenger that operates through different signaling molecules, including protein kinase A (PKA) and guanine exchange proteins directly activated by cAMP (EPAC). Cell-permeable cAMP analogs such
Gerlo, Sarah +6 more
core +1 more source
Comprehensive Analysis of Soluble Mediator Profiles in Congenital CMV Infection Using an MCMV Model
VirusesCongenital human cytomegalovirus (HCMV) infection may cause life-threatening disease and permanent damage to the central nervous system. The mouse model of CMV infection is most commonly used to study mechanisms of infection and pathogenesis.
Dubravka Karner +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection
, 2011 Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Nashwa Abousamra +5 more
core
Case Report: Mycoplasma pneumoniae–associated acute pancreatitis
Frontiers in PediatricsMycoplasma pneumoniae is the primary pathogen causing community-acquired pneumonia in children, accounting for approximately 10%–40% of cases. It can lead to various extrapulmonary complications, including acute pancreatitis, which has been reported in ...
Hong Sun +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source