Results 151 to 160 of about 1,857,465 (364)

Apoptosis-induced tolerance. Role of the novel cytokine IL-38

, 2022
S.109-110Introduction: Necrotic cell death triggers inflammation, whereas apoptosis contributes to its resolution. Interleukin-1 (IL-1) family cytokines are key players in this interaction and are produced by necrotic cells to induce sterile inflammation.
Putyrski, M., Brüne, B., Han, Y., Wittig, I., Ernst, A., Mora, J., Weigert, A.   +6 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Cytokine responses of human gingival fibroblasts to Actinobacillus actinomycetemcomitans cytolethal distending toxin

, 2005
Actinobacillus actinomycetemcomitans is implicated in the pathogenesis of localized aggressive periodontitis, and has the capacity to express a cytolethal distending toxin (Cdt). Gingival fibroblasts (GF) are resident cells of the periodontium, which can
C. Chen, A. Johansson, Lagergård, T, Lerner, Ulf,, Wang, Y, Kalfas, S, G.N. Belibasakis, Belibasakis, Georgios N,, Lagergård, Teresa,, Belibasakis, G N, T. Lagergård, Lerner, Ulf H,, U.H. Lerner, Johansson, Anders,, S. Kalfas, Chen, C, Y. Wang, Johansson, A   +17 more
core   +1 more source

Roles of Inflammasome and Cytokines in the Pathogenesis of Autoimmune Thyroiditis

The Turkish Journal of Ear Nose and Throat
Objective: In this study, we aimed to investigate the role of the NLRP3 inflammasome, pro- and antiinflammatory cytokines, and their correlations in the pathogenesis of HT. Material and Methods: The pro-inflammatory cytokine tumour necrosis factor alpha (
Gülten Ateş, İsmail Cem Sormaz
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Recombinant SAG2A Protein from Toxoplasma gondii Modulates Immune Profile and Induces Metabolic Changes Associated with Reduced Tachyzoite Infection in Peritoneal Exudate Cells from Susceptible C57BL/6 Mice

Microorganisms
Toxoplasmosis is a neglected disease that represents a significant public health problem. The antigenic profile of T. gondii is complex, and the immune response can lead to either susceptibility or resistance.
Thaíse Anne Rocha dos Santos, Mário Cézar de Oliveira, Edson Mario de Andrade Silva, Uener Ribeiro dos Santos, Monaliza Macêdo Ferreira, Ana Luísa Corrêa Soares, Neide Maria Silva, Tiago Antônio de Oliveira Mendes, Jamilly Azevedo Leal-Sena, Jair Pereira da Cunha-Júnior, Tiago Wilson Patriarca Mineo, José Roberto Mineo, Érica Araújo Mendes, Jane Lima-Santos, Carlos Priminho Pirovani   +14 more
doaj   +1 more source

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.

Cell, 1998
D. Lacey, E. Timms, H. Tan, M. Kelley, C. Dunstan, Tim Burgess, R. Elliott, A. Colombero, G. Elliott, S. Scully, H. Hsu, J. Sullivan, N. Hawkins, E. Davy, C. Capparelli, Alana G. Eli, Y. Qian, S. Kaufman, I. Sarosi, V. Shalhoub, G. Senaldi, Jane Guo, J. Delaney, W. J. Boyle   +23 more
semanticscholar   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Dynamics of cytokine mRNA expression and fecal biomarkers in school-children undergoing a double-blind placebo-controlled food challenge series

, 2016
Background: There is need for prognostic markers for symptomatic food allergy since current diagnostic methods are insufficient and/or time and labor consuming. Objective: To estimate the cytokine mRNA profiles in peripheral blood mononuclear cells (PBMC)
Nagaeva, Olga,, Nagaev, Ivan,, Rönmark, Eva,, Winberg, Anna,, Lundell, Catarina,, Arencibia, Ignacio,, West, Christina,, Mincheva Nilsson, Lucia,   +7 more
core   +1 more source