Results 161 to 170 of about 3,715,994 (387)

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

From Large to Small Cytokine Receptor Antagonists

SLAS Discovery
Here, we review general trends in biological and small molecule cytokine drug discovery, highlighting key learnings from two successful case studies (TNFα and IL-17), which have helped shape our understanding of how best to identify new small molecule ...
Pawel Leznicki, Karl Deacon, Bohdan Waszkowycz, John F Unitt   +3 more
doaj   +1 more source

Serum cytokines and their soluble receptors are differently regulated between trained and untrained men after vigorous endurance exercise [PDF]

Jeremy B. Ducharme, Jonathan W. Specht, Alyssa R. Bailly, Michael R. Deyhle   +3 more
openalex   +1 more source

Transmembrane Protein Aptamer Induces Cooperative Signaling by the EPO Receptor and the Cytokine Receptor β-Common Subunit [PDF]

, 2019
He Li, Emily B. Cohen, Anne P. B. Edwards, Juliana Xavier-Ferrucio, Katrine Bugge, Ross S. Federman, Devin Absher, R Myers, Birthe B. Kragelund, Diane S. Krause, Daniel DiMaio   +10 more
openalex   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma. [PDF]

Blood Adv, 2023
Brownlie RJ, Kennedy R, Wilson EB, Milanovic M, Taylor CF, Wang D, Davies JR, Owston H, Adams EJ, Stephenson S, Caeser R, Gewurz BE, Giannoudis PV, Scuoppo C, McGonagle D, Hodson DJ, Tooze RM, Doody GM, Cook G, Westhead DR, Klein U.   +20 more
europepmc   +1 more source

Brain cytokines and their receptors: expression and functions

, 1995
Masamichi Satoh, Yasuko Tomozawa, Masabumi Minami, Kazuki Yabuuchi, Seishi Katsumata, Takahito lnoue   +5 more
openalex   +1 more source

The Common Cytokine Receptor γ Chain Controls Survival of γ/δ T Cells [PDF]

, 1997
Marie Malissen, Pablo Pereira, David J. Gerber, Bernard Malissen, James P. Di Santo   +4 more
openalex   +1 more source

Topical Tacrolimus in Patients with Hands Eczema Taking into Account the Severity of Dermatoses, Some Cytokine Profile Indicators, Content of Vitamin D and Genetic Polymorphism of the Glucocorticoid Receptor Gene [PDF]

, 2021
A. M. Methkal
openalex   +1 more source

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes

Science, 2018
Jonathan T. Sockolosky, E. Trotta, Giulia Parisi, Lora K. Picton, L. Su, Alan C. Le, Akanksha Chhabra, Stephanie Silveria, Benson M. George, I. King, Matthew R. Tiffany, K. Jude, L. Sibener, D. Baker, Judith A. Shizuru, A. Ribas, J. Bluestone, K. C. Garcia   +17 more
semanticscholar   +1 more source