Human granulocytes contain an opiate alkaloid-selective receptor mediating inhibition of cytokine-induced activation and chemotaxis. [PDF]
Maynard H. Makman+2 more
openalex +1 more source
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
Sequential control of myeloid cell proliferation and differentiation by cytokine receptor-based chimeric antigen receptors. [PDF]
Nakajima K+4 more
europepmc +1 more source
Cytokine regulation of low density lipoprotein receptor gene transcription in HepG2 cells
Alison Stopeck+3 more
openalex +1 more source
IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition. [PDF]
David G. Alleva+4 more
openalex +1 more source
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
Redirecting immune signaling with cytokine adaptors
Cytokines are signaling molecules that coordinate complex immune processes and are frequently dysregulated in disease. While cytokine blockade has become a common therapeutic modality, cytokine agonism has had limited utility due to the widespread ...
Gita C. Abhiraman+12 more
doaj +1 more source
The Carboxyl-terminal Domains of gp130-related Cytokine Receptors Are Necessary for Suppressing Embryonic Stem Cell Differentiation [PDF]
Matthias Ernst+4 more
openalex +1 more source