Results 201 to 210 of about 517,948 (338)

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Insulin Receptor Substrate-2 Is the Major 170-kDa Protein Phosphorylated on Tyrosine in Response to Cytokines in Murine Lymphohemopoietic Cells [PDF]

, 1997
Melanie J. Welham, Heather K. Bone, Megan K. Levings, Leslie Learmonth, Lingmei Wang, Kevin B. Leslie, Jacalyn H. Pierce, John W. Schrader   +7 more
openalex   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

Advanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han, Godfrey Mwiti, Seo‐Joon Yeom, Jaeyoon Lim, Woo Sik Kim, Sangyong Lim, Seung‐Taik Lim, Eui‐Baek Byun   +7 more
wiley   +1 more source

Cytokine receptor-like factor 1 (CRLF1) promotes cardiac fibrosis via ERK1/2 signaling pathway. [PDF]

J Zhejiang Univ Sci B, 2023
Luo S, Yang Z, Chen R, You D, Teng F, Yuan Y, Liu W, Li J, Zhang H.   +8 more
europepmc   +1 more source

Modulation of cytokine expression by CD4+ T cells during coxsackievirus B3 infections of BALB/c mice initiated by cells expressing the gamma delta + T-cell receptor [PDF]

, 1996
Sally A. Huber, A Mortensen, Gerald Moulton   +2 more
openalex   +1 more source

Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment

Advanced Healthcare Materials, EarlyView.
These findings advance tissue repair by offering a multifunctional filler that improves large‐scale volume retention, elasticity, and support for vascularized tissue growth. The decellularized extracellular matrix (dECM)‐based material provides low injection force and minimizes swelling, ensuring sustained volume. Combining CMC with supercritical fluid‐
Seol‐Ha Jeong, Jae Jun Kang, Ki‐Myo Kim, Mi hyun lee, Misun Cha, Su Hee Kim, Ji‐Ung Park   +6 more
wiley   +1 more source

De novo-designed transmembrane proteins bind and regulate a cytokine receptor. [PDF]

Nat Chem Biol
Mravic M, He L, Kratochvil HT, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF.   +10 more
europepmc   +1 more source

Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution. [PDF]

Nat Commun, 2021
Lima LG, Ham S, Shin H, Chai EPZ, Lek ESH, Lobb RJ, Müller AF, Mathivanan S, Yeo B, Choi Y, Parker BS, Möller A.   +11 more
europepmc   +1 more source

Guidebook to cytokines and their receptors [PDF]

, 1995
Marco Baggiolini
openalex   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

Advanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li, Andi Dian Permana, Juan Domínguez‐Robles, Muh Nur Amir, Habibie Habibie, Qonita Kurnia Anjani, Li Zhao, Natalia Moreno‐Castellanos, Ryan F Donnelly, Eneko Larrañeta   +9 more
wiley   +1 more source