Results 51 to 60 of about 3,715,994 (387)

Virus encoded cytokines and cytokine receptors

open access: yesParasitology, 1997
In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of
M, Barry, G, McFadden
openaire   +2 more sources

De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18).

open access: yes, 2004
Complementary (antisense) peptide mini-receptor inhibitors are complementary peptides designed to be receptor-surrogates that act by binding to selected surface features of biologically important proteins thereby inhibiting protein-cognate receptor ...
Bhakoo, Ashish   +4 more
core   +1 more source

Cell Surface Markers in HTLV-1 Pathogenesis

open access: yesViruses, 2011
The phenotype of HTLV-1-transformed CD4+ T lymphocytes largely depends on defined viral effector molecules such as the viral oncoprotein Tax. In this review, we exemplify the expression pattern of characteristic lineage markers, costimulatory receptors ...
Andrea K. Kress   +2 more
doaj   +1 more source

Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor

open access: yesFrontiers in Immunology, 2021
Interleukin-1 (IL-1) family cytokines are potent mediators of inflammation, acting to coordinate local and systemic immune responses to a wide range of stimuli. Aberrant signaling by IL-1 family cytokine members, however, is linked to myriad inflammatory
James K. Fields   +16 more
doaj   +1 more source

Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar) [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Martin, Samuel A.M.   +3 more
core   +2 more sources

Cytokine Receptor Endocytosis: New Kinase Activity-Dependent and -Independent Roles of PI3K

open access: yesFrontiers in Endocrinology, 2017
Type I and II cytokine receptors are cell surface sensors that bind cytokines in the extracellular environment and initiate intracellular signaling to control processes such as hematopoiesis, immune function, and cellular growth and development.
Lily Jun-shen Huang   +2 more
doaj   +1 more source

Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor. [PDF]

open access: yesPLoS ONE, 2011
Length and intensity of signal transduction via cytokine receptors is precisely regulated. Degradation of certain cytokine receptors is mediated by the ubiquitin ligase SCF(βTrCP).
Joyce Putters   +5 more
doaj   +1 more source

RAGE Signaling in Skeletal Biology [PDF]

open access: yes, 2019
PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M.   +2 more
core   +2 more sources

Modeling Cell-to-Cell Communication Networks Using Response-Time Distributions. [PDF]

open access: yes, 2018
Cell-to-cell communication networks have critical roles in coordinating diverse organismal processes, such as tissue development or immune cell response. However, compared with intracellular signal transduction networks, the function and engineering
Altschuler, Steven J   +2 more
core   +2 more sources

Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes

open access: yesFrontiers in Immunology, 2018
Interleukin (IL)-4 and IL-13 are related cytokines that regulate many aspects of allergic inflammation. They play important roles in regulating the responses of lymphocytes, myeloid cells, and non-hematopoietic cells.
I. Junttila
semanticscholar   +1 more source

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