Results 171 to 180 of about 71,915 (261)

Inulin‐Butyrate Nanogel for Modulation of Gut Microbiome, Intestinal Barrier, and Regulatory T‐Cells in Colitis

Small, EarlyView.
ABSTRACT Inflammatory bowel diseases (IBD) arise from a vicious cycle of intestinal barrier dysfunction, gut microbiome dysbiosis, and dysregulated immune responses. Current therapies predominantly suppress immunity but fail to address root causes or break this cycle.
Nayoon Park, Bom Lee, Hyeon‐Jeong Jeon, Ji Yeon Kim, Suyeon Park, Seong‐Eun Kim, Dong‐Kyu Lee, Yonghyun Lee   +7 more
wiley   +1 more source

Early prediction and warning of MODS following major trauma via identification of cytokine storm: A prospective cohort study. [PDF]

Chin J Traumatol
Chang P, Li R, Wen J, Liu G, Jin F, Yu Y, Li Y, Zhang G, Wang T.   +8 more
europepmc   +1 more source

Self‐Healing and pH‐Robust Hydrogels Enabled by Synergistic Supramolecular Interactions for Injectable Gastrointestinal Wound Repair

Small, EarlyView.
A pH‐robust injectable hydrogel enabled by synergistic supramolecular interactions is developed to address the intrinsic limitations of conventional hydrogel dressings in complex gastrointestinal environments. By actively leveraging environmental stimuli to regulate functionality, this supramolecular synergy strategy provides a versatile platform for ...
Li Xiang, Lei Liu, Shixin Zhang, Yuhao Zhang, Ziqian Zhao, Jiangwei Chen, Jiawen Zhang, Jingyi Hu, Yunfei Chen, Hongbo Zeng   +9 more
wiley   +1 more source

Tenofovir attenuates cytokine storm and bronchiolar damage in a mouse model of bleomycin-induced acute lung injury. [PDF]

Sci Rep
López IP, Romero L, Alfaro-Arnedo E, Canalejo M, Pichel JG, Blanco JR, Pérez-Martínez L.   +6 more
europepmc   +1 more source

Spatiotemporal Co‐Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi‐Modal In Vivo Study

Small, EarlyView.
A spatiotemporal co‐delivery microneedle system (MN‐Mg) is developed for spinal cord injury repair. By generating hydrogen gas and magnesium ions in situ, this dual‐engine platform effectively scavenges ROS and modulates microglial polarization via the MAPK/AP‐1 signaling axis.
Haibo Wang, Yang Sun, Shiqi Wang, Wenbo Wang, Jincheng Tang, Ziang Li, Xinzhao Jiang, Liang Zhou, Jie Wu, Qiangqiang Guo, Yiwei Zhu, Yu Feng, Kun Xi, Liang Chen   +13 more
wiley   +1 more source

Transcriptomic evidence of cytokine storm and sepsis in little brown bats exposed to white-nose syndrome. [PDF]

Conserv Physiol
Kwait RE, Eskew EA, Pinsky ML, Gignoux-Wolfsohn SA, Vonhof MJ, Maslo B.   +5 more
europepmc   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Angiopoietin-like protein 8 orchestrates macrophage glycogen metabolism and polarization via the JNK signaling pathway in cytokine storm syndrome. [PDF]

Cell Biosci
Su Y, Zhang R, Li K, Shen H, Nan M, Liu C, Zhang W, Chen S.   +7 more
europepmc   +1 more source

Data privacy model using blockchain reinforcement federated learning approach for scalable internet of medical things

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Internet of Medical Things (IoMT) has typical advancements in the healthcare sector with rapid potential proof for decentralised communication systems that have been applied for collecting and monitoring COVID‐19 patient data. Machine Learning algorithms typically use the risk score of each patient based on risk factors, which could help ...
Chandramohan Dhasaratha, Mohammad Kamrul Hasan, Shayla Islam, Shailesh Khapre, Salwani Abdullah, Taher M. Ghazal, Ahmed Ibrahim Alzahrani, Nasser Alalwan, Nguyen Vo, Md Akhtaruzzaman   +9 more
wiley   +1 more source

Fatal Influenza B-MRSA Coinfection in a Healthy Adolescent: Necrotizing Pneumonia, Cytokine Storm, and Multi-Organ Failure. [PDF]

Children (Basel)
Profir I, Popescu CM, Nechita A.
europepmc   +1 more source