Results 241 to 250 of about 2,687,827 (299)

The carbohydrate recognition by cytokines modulates their physiological activities

Glycoconjugate Journal, 2004
A variety of cytokines have been reported to be able to recognize specific carbohydrate moieties. To date, the role of carbohydrate recognition in cytokine function has been analyzed for several cytokines, including fibroblast growth factor (FGF), tumor necrosis factor (TNF)-alpha, and interleukin (IL)-2.
Katsuko, Yamashita, Keiko, Fukushima
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Autocrine secretion and the physiological concentration of cytokines

Immunology Today, 1996
Abstract In contrast to hormones, cytokine activities are often purely local and, consequently, their active physiological concentration is hard to define. Here, using IL-2 as an example, David Kaplan proposes that the local concentrations of cytokines might be much greater than expected.
openaire   +2 more sources

[Cytokines and pregnancy: physiology].

Journal de gynecologie, obstetrique et biologie de la reproduction, 1992
Several biological systems originating in the fetus and in the mother are involved in embryo implantation, maintenance of the pregnancy, protection of the fetus against outside influences and the start of labour (these are the immune system, endocrine system, and the endothelial system).
D, Vinatier, O, Tiffet, P, Dufour, B, Tiberghien, C, Maunoury-Lefebvre, J C, Monnier   +5 more
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Neutrophil-Derived Cytokines Involved in Physiological and Pathological Angiogenesis

2013
Increasing data from the literature point to a neutrophil-mediated role via cytokine production in several aspects of mammalian biology, including angiogenesis. In such regard, neutrophils have been shown to synthetize and release a number of molecules able to promote, directly or indirectly, the growth and migration of endothelial cells, in turn ...
TECCHIO, Cristina, CASSATELLA, Marco Antonio   +1 more
openaire   +2 more sources

Immunosuppressants: Tools to investigate the physiological role of cytokines

BioEssays, 1993
AbstractThe cyclic opeptide Cyclosporinee A (CsA) is best known as the immunosuppressive drug which has revoulutionized organ transplantation. It selectively suppresses T cell activation by blocking the transcription of cytokine genes such as IL‐2 at the level of transxcription factor modulation.
openaire   +2 more sources

Extracellular matrix communication and turnover in cardiac physiology and pathology.

Comprehensive Physiology, 2015
Despite significant advances in treating heart disease, heart failure remains a major cause of morbidity and mortality. Regardless of the initiating cause(s), heart failure is associated with disruptions in the myocardial extracellular matrix (ECM).
A. Takawale, S. S. Sakamuri, Z. Kassiri
semanticscholar   +1 more source

Cytokines and Hematopoietins: Physiology, Pathophysiology, and Potential as Therapeutic Agents

1991
Improved understanding of host biology, immunology, and tumor pathophysiology raises the possibility of introducing new treatment modalities for cancer patients: stimulation of host defense mechanisms, including specific and nonspecific immunological approaches, as well as approaches aimed directly at altering tumor growth and differentiation by ...
R, Mertelsmann, F M, Rosenthal, A, Lindemann, F, Herrmann   +3 more
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[The ovaries, the immune system, cytokines: physiology].

Journal de gynecologie, obstetrique et biologie de la reproduction, 1994
Sevellar cellular types are involved together in the cyclical functioning of the ovary. Regulating this co-operation between cells are intercellular systems of communication both autocrine and paracrine. The immune system that is present in the ovary seems to have an important role among the regulatory factors.
D, Vinatier, C, Lefebvre-Maunoury, C, Bernardi   +2 more
openaire   +1 more source

PHYSIOLOGIC STATE SEVERITY CLASSIFICATION AS AN INDICATOR OF POSTTRAUMA CYTOKINE RESPONSE

Shock, 1995
A Physiologic State Severity Classification (PSSC) derived from clustering of 17 cardiorespiratory variables was used to predict cytokine response in critically ill posttrauma patients. The PSSC defined physiologic states: A-State (A), normal stress response; B-State (B), metabolic insufficiency; C2-State (C), respiratory insufficiency.
D, Rixen, J H, Siegel, A, Abu-Salih, M, Bertolini, F, Panagakos, N, Espina   +5 more
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CX3CL1 (Fractalkine): An important cytokine in physiological and pathological pregnancies

Journal of Reproductive Immunology
C-X3-C motif chemokine ligand 1 (CX3CL1), commonly known as Fractalkine, is an important chemokine with dual functions of chemotaxis and adhesion. It plays a pivotal role in a variety of physiological processes and pathological conditions, particularly in conjunction with its receptor, C-X3-C motif chemokine receptor 1 (CX3CR1).
Xianyang, Hu, Xixi, Huang, Tingxuan, Yin, Jiajia, Chen, Weijie, Zhao, Min, Yu, Lu, Liu, Meirong, Du   +7 more
openaire   +2 more sources