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Cytokines in placental physiology
Advances in Neuroimmunology, 1991Recent studies have shown that the human placenta is a very complex organ with many properties (Petraglia et al., 1990c). It plays a very important role in the physiology of pregnancy. Among various functions, its hormonal production is one of the most relevant.
Angioni, S. +7 more
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Cytokines and Skeletal Physiology
Clinical Orthopaedics and Related Research, 1996Cytokines are soluble factors that play a critical role in mediating cell to cell interactions within skeletal tissues. These effects are mediated by paracrine, autocrine, and juxtacrine mechanisms. There are also examples in which the cytokines can function in an endocrine fashion.
S R, Goldring, M B, Goldring
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SOCS: physiological suppressors of cytokine signaling
Journal of Cell Science, 2000ABSTRACT Cytokines regulate cellular behavior by interacting with receptors on the plasma membrane of target cells and activating intracellular signal transduction cascades such as the JAK-STAT pathway. Suppressors of cytokine signaling (SOCS) proteins negatively regulate cytokine signaling.
D L, Krebs, D J, Hilton
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Humoral regulation of physiological sleep: cytokines and GHRH
Journal of Sleep Research, 1999Interleukin‐1, tumour necrosis factor, and growth hormone releasing hormone form part of the humoral mechanisms regulating physiological sleep. Their injection enhances non‐rapid‐eye‐movement sleep whereas their inhibition reduces spontaneous sleep and sleep rebound after sleep deprivation.
J M, Krueger, F, Obál, J, Fang
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Physiological role of cytokines in the regulation of mammalian metabolism
Trends in Immunology, 2023The innate cytokine system is involved in the response to excessive food intake. In this review, we highlight recent advances in our understanding of the physiological role of three prominent cytokines, interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF), in mammalian metabolic regulation.
Axel de Baat +3 more
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The Role of Cytokines in Physiological Sleep Regulation
Annals of the New York Academy of Sciences, 2001Abstract: Several growth factors (GFs) are implicated in sleep regulation. It is posited that these GFs are produced in response to neural activity and affect input‐output relationships within the neural circuits where they are produced, thereby inducing a local state shift. These GFs also influence synaptic efficacy.
J M, Krueger +4 more
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The Cytokines: Physiological and Pathophysiological Aspects
1993Publisher Summary This chapter discusses the physiological and pathophysiological aspects of cytokines. Despite the fact that many of the molecules are described on the basis of a single biological function, several molecules subsequently turned out to be pleiotropic with a wide range of actions and target cells.
S W, Evans, J T, Whicher
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The carbohydrate recognition by cytokines modulates their physiological activities
Glycoconjugate Journal, 2004A variety of cytokines have been reported to be able to recognize specific carbohydrate moieties. To date, the role of carbohydrate recognition in cytokine function has been analyzed for several cytokines, including fibroblast growth factor (FGF), tumor necrosis factor (TNF)-alpha, and interleukin (IL)-2.
Katsuko, Yamashita, Keiko, Fukushima
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