Results 91 to 100 of about 26,266 (223)

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea, De Baetselier, Patrick, De Trez, Carl, Korf, Hannelie, Magez, Stefan, Stijlemans, Benoit, Van Ginderachter, Jo A   +6 more
core   +1 more source

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe, Tamara Zoran, Marylyn Martina Addo   +2 more
wiley   +1 more source

High dilutions of antimony modulate cytokines production and macrophage – Leishmania (L.) amazonensis interaction in vitro

Cytokine, 2017
In previous results mice treated with high dilutions of antimony presented reduction of monocyte migration to the site of infection with increase in B lymphocytes population in the local lymph node.To know the mechanisms involved, a series of in vitro studies was done, using co-cultures of macrophages (RAW 264.7) and Leishmania (L.) amazonensis treated
Fabiana Rodrigues, de Santana, Luciane C, Dalboni, Kátia F, Nascimento, Fabiana Toshie, Konno, Anuska M, Alvares-Saraiva, Michelle S F, Correia, Maristela Dutra Correa, Bomfim, Renato C V, Casarin, Elizabeth C, Perez, Maria Anete, Lallo, Giovani B, Peres, Márcia Dalastra, Laurenti, Nilson R, Benites, Dorly F, Buchi, Leoni Villano, Bonamin   +14 more
openaire   +2 more sources

Dog skin parasite load, TLR-2, IL-10 and TNF-α expression and infectiousness [PDF]

, 2017
Visceral leishmaniosis is a zoonotic disease that is transmitted by Lutzomyia longipalpis sandflies. Dogs are the main peri-urban reservoir of the disease, and progression of canine leishmaniosis is dependent on the type of immune response elaborated ...
Avanço, S. V., Beloti, C. A. C., Calvo-Bado, Leo A., Cipriano, R. S., Courtenay, Orin, Hiramoto, R. M., Ito, P. K. R. K., Lima, V. M. F., Machado, G. F., Nunes, C. M., Oliveira-Rovai, F. M., Pereira-Fonseca, D. C. M., Rodas, L. A. C., Torrecilha, R. B. P., Utsunomiya, Y. T.   +14 more
core   +1 more source

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensisto nitric oxide correlates with disease severity in Tegumentary Leishmaniasis [PDF]

, 2007
Background Nitric oxide (NO•) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO• resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases.
Angela Giudice, Ilza Camada, Paulo TG Leopoldo, Júlia MB Pereira, Lee W Riley, Mary E Wilson, John L Ho, Amelia Ribeiro de Jesus, Edgar M Carvalho, Roque P Almeida, AL Bittencourt, H Louzir, M Castes, PD Marsden, JM Costa, J Alexander, J Alexander, FY Liew, P Scott, ME Wilson, FY Liew, FY Liew, C Bogdan, SJ Green, TG Evans, J Assreuy, HW Murray, S Nicholson, KR Gantt, C Bogdan, J Mauel, PR Romao, WJ Paramchuk, SR Meshnick, TJ Vickers, MP Levick, MA Miller, FC Fang, E Cupolillo, ME Wilson, C Bogdan, HW Murray, NE Reiner, P Scott, I Vouldoukis, P Kumar, C Bogdan, M Barral-Netto, ME Wilson, E Cupolillo, SM Cupolilo, A Schriefer, KA Rockett, I Vouldoukis, NK Basu, M Genestra, M Genestra, R Hanano, K Kawakami, DR Pakianathan, FM Balestieri, A Descoteaux, C Nathan, A Jardim   +63 more
core   +1 more source

Honokiol and Magnolol Exert an Anti‐Inflammatory Effect by Inhibiting JAK2/STAT3/IL17 Signalling in a Rat Model of Ulcerative Colitis: A Combination of Bioinformatics and Experimental Study

Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Ulcerative colitis (UC) is a chronic, inflammatory bowel disease with limited clinical treatment. Traditional Chinese medicinal ingredients honokiol and magnolol have potential anti‐inflammatory and gastrointestinal protective effects. However, their anti‐inflammatory potential has not been investigated in UC.
Zhaoxu Cai, Shaojun Lu, Jingan Chen, Xiaoshan Yang, Junlin Lu, Changwen Feng   +5 more
wiley   +1 more source

Cytokine and transcription factor profiles in the skin of dogs naturally infected by Leishmania (Leishmania) chagasi presenting distinct cutaneous parasite density and clinical status

Veterinary Parasitology, 2011
The immune response in the skin of dogs infected with Leishmania chagasi and its association with distinct levels of tissue parasitism and clinical progression of canine visceral leishmaniasis (CVL) are poorly understood and limited studies are available.
Menezes-Souza, Daniel, Corrêa-Oliveira, Rodrigo, Guerra-Sá, Renata, Giunchetti, Rodolfo Cordeiro, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Oliveira, Guilherme Corrêa, Reis, Alexandre Barbosa   +7 more
openaire   +2 more sources

Organic Light‐Emitting Diode in Phototherapy Applications

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
This article systematically reviews the development of organic light‐emitting diodes (OLEDs) in phototherapy, constructs a technical framework, and establishes a multidimensional knowledge graph encompassing indications, wavelengths, and light intensity.
Yingguang Zhu, Yonglan Hu, Yingjie Cui, Lixue Guo, Guohui Zhang, Haixia Qiu, Defu Chen, Changyong Pan, Huijuan Yin, Suling Zhao   +9 more
wiley   +1 more source

T helper1/T helper2 cells and resistance/susceptibility to Leishmania infection: is this paradigm still relevant?

Frontiers in Immunology, 2012
Work in large part on Leishmania major in the 1980s identified two distinct apparently counter-regulatory CD4+ T cell populations, T helper (h)1 and Th2, that controlled resistance/susceptibility to infection respectively. However, the generation of IL-4-
James eAlexander, Frank eBrombacher
doaj   +1 more source