Increased levels of IL-10, IL-12, and IFN-in patients with visceral leishmaniasis [PDF]
, 2009 Visceral leishmaniasis remains a serious public health problem in developing countries. Cytokines have a crucial role in the pathogenesis of this disease.
Abdolvahab, Alborz. +5 more
core +1 more source
Chemical and Biological Properties of Hymenaea courbaril L.: A Review
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.PRISMA‐style flowchart showing the screening process of studies identified and selected in the review has been added to the attachments. ABSTRACT Hymenaea courbaril L., commonly known as jatobá, is a plant traditionally used by native populations for medicinal purposes, in addition to providing edible fruits and durable wood for construction.
Cicera Alane Coelho Gonçalves +6 more
wiley +1 more source
Cell Reports, 2016 Participation of B cells in the immune response by various antibody-independent mechanisms has recently been uncovered. B cells producing cytokines have been described for several infections and appear to regulate the adaptive immune response.
Sasha Silva-Barrios +6 more
doaj +1 more source
Immunological relationships during primary infection with Heligmosomoides polygyrus (Nematospiroides dubius): downregulation of specific cytokine secretion (IL-9 and IL-10) correlates with poor mastocytosis and chronic survival of adult worms [PDF]
, 1993 Mice were infected either with Trichinella spiralis (day 0), Heligmosomoides polygyrus (day -14) or concurrently with both species and were killed in groups, together with naive control mice, on 2 occasions (day 8 and 15 post infection with T.
Behnke, Jerzy M. +5 more
core +2 more sources
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
Immunology, Volume 177, Issue 2, Page 254-269, February 2026.We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites
Frontiers in Immunology, 2018 Activated natural killer (NK) cells release interferon (IFN)-γ, which is crucial for the control of intracellular pathogens such as Leishmania. In contrast to experimental murine leishmaniasis, the human NK cell response to Leishmania is still poorly ...
Helena Messlinger +8 more
doaj +1 more source
Activation of human NK cells by Plasmodium-infected red blood cells.
, 2012 This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Horowitz, Amir, Riley, Eleanor M
core +1 more source
Cytokine profiles amongst Sudanese patients with visceral leishmaniasis and malaria co-infections [PDF]
, 2014 Background The immune system plays a critical role in the development of co-infections, promoting or preventing establishment of multiple infections and shaping the outcome of pathogen-host interactions.
Adams, Emily
core +1 more source
Parasitology, 2014 SUMMARYIn the present study, we assessed morphological changes and cytokine production afterin vitrointeraction with causative agents of American cutaneous leishmaniasis and compared the microglia and macrophage immune responses. Cultures of microglia and macrophages infected with stationary-phase promastigotes ofLeishmania(Viannia)shawi, Leishmania ...
Patricia Karla Santos, Ramos +6 more
openaire +2 more sources
Prophylactic properties of a Leishmania-specific hypothetical protein in a murine model of visceral leishmaniasis [PDF]
, 2016 In this work, the effect of vaccination of a newly described Leishmania infantum antigenic protein has been studied in BALB/c mice infected with this parasite species.
Chávez-Fumagalli, Miguel A. +9 more
core +1 more source