Results 111 to 120 of about 26,266 (223)

Cytotoxic and Antileishmanial Potential of Pilocarpus microphyllus Essential Oil: In Vitro and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Jaborandi (Pilocarpus microphyllus) essential oil is obtained by removal and characterization using GC‐MS, revealing γ‐cadinene and trans‐caryophyllene as major constituents. The oil exhibits biological activity, with antifungal action against Candida spp.
Juniel Cruz Silva, Maria Gabriela Araújo Mendes, Paulo Sérgio de Araujo Sousa, Alyne Rodrigues de Araújo Nobre, Michel Muálem de Moraes Alves, Fernando Aécio de Amorim Carvalho, Tatiane Caroline Daboit, José de Sousa Lima Neto, Ygor Victor Ferreira Pinheiro, Ytallo da Costa Sousa, Edymilaís da Silva Sousa, José Delano Barreto Marinho Filho, Ana Jérsia Araújo, Francisco Artur Silva Filho, Sidney Gonçalo de Lima, Leiz Maria Costa Véras   +15 more
wiley   +1 more source

Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.

PLoS ONE, 2016
Dogs represent the most important domestic reservoir of L. chagasi (syn. L. infantum). A vaccine against canine visceral leishmaniasis (CVL) would be an important tool for decreasing the anxiety related to possible L.
Lucilene Aparecida Resende, Rodrigo Dian de Oliveira Aguiar-Soares, Henrique Gama-Ker, Bruno Mendes Roatt, Ludmila Zanandreis de Mendonça, Marina Luiza Rodrigues Alves, Denise da Silveira-Lemos, Rodrigo Corrêa-Oliveira, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo, Ricardo Toshio Fujiwara, Nelder Figueiredo Gontijo, Alexandre Barbosa Reis, Rodolfo Cordeiro Giunchetti   +13 more
doaj   +1 more source

Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]

, 2005
Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines, Ilarregui, Juan Martin, Rabinovich, Gabriel Adrián, Rubinstein, Natalia, Sanjuan, Norberto Aníbal, Toscano, Marta Alicia   +5 more
core   +1 more source

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]

, 1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB, Erle, DJ, Folkesson, HG, Locksley, RM, Matthay, MA, Warnock, ML, Wiener-Kronish, JP   +6 more
core  

Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response. [PDF]

, 2016
Many Leishmania (Viannia) parasites harbor the double-stranded RNA virus Leishmania RNA virus 1 (LRV1), which has been associated with increased disease severity in animal models and humans and with drug treatment failures in humans.
Akopyants, N.S., Beverley, S.M., Brettmann, E.A., Fasel, N., Hickerson, S.M., Kuhlmann, F.M., Lye, L.F., Oschwald, D.M., Owens, K.L., Ronet, C., Shaik, J.S., Zangger, H.   +11 more
core   +2 more sources

Effects of tropism and virulence ofLeishmaniaparasites on cytokine production by infected human monocytes

Clinical and Experimental Immunology, 2008
SummaryThe nature of early interactions between Leishmania and macrophages which determine the outcome of infection can be related directly to parasite biological properties. Here we compared the capacity of L. major (Lm) strains, reported to be high (LmHV) and low virulent and (LmLV) in the mouse model and L.
A, Meddeb-Garnaoui, H, Zrelli, K, Dellagi   +2 more
openaire   +3 more sources

Immunotherapy for Visceral Leishmaniasis: Ability of Factors Produced during Anti-leishmania Responses of Skin Test Positive Adults to Inhibit Peripheral Blood Mononuclear Cell Activities Associated with Visceral Leishmaniasis

Memorias do Instituto Oswaldo Cruz, 1999
The course of human Leishmania chagasi infections appears to be determined by the balance between type 1 (T1) CD4+ and CD8+ T suppressor (Ts) cell activities.
Holaday Bettie J
doaj  

B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response [PDF]

, 2013
We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection. The present study examined the mechanisms by
A Casadevall, A Cruz, A Glatman-Freedman, AM Cooper, AR Martineau, B Nandi, C Diveu, C Keller, CE Sutton, CG Feng, Christopher M. Sassetti, CJ Thalhofer, CY Hu, D Kitamura, DB Rawool, DJ Cua, DV Jovanovic, E Lockhart, E Marino, E Roy, E Torrado, EB Eruslanov, FE Lund, FL Ribeiro-Gomes, J Hinchey, J Pedrosa, Jiayong Xu, JL Flynn, JM Daley, Joanne L. Flynn, John Chan, JS Thorson, JU Igietseme, K Dunussi-Joannopoulos, K Hamel, KA Sweeney, Kyri Dunussi-Joannopoulos, L Desvignes, L Li, Lee Kozakiewicz, LJ Brady, M Cella, M Laan, M Zhang, MC Tsai, ML Michel, NK Damle, P Miossec, P Seiler, P Ye, PJ Maglione, PJ Maglione, PJ Maglione, PR Hamann, PS Redford, Qinglin Ou, R Appelberg, R Blomgran, R Gopal, RJ North, SA Fulton, SA Khader, ST Passos, Steven A. Porcelli, T Eddens, T Hamilton, T Korn, T Matsushita, TK Kondratieva, W Ouyang, William R. Jacobs, X Zhang, Y Ito, Yanhua Wang, Yong Chen   +74 more
core   +3 more sources

Atypical presentation of visceral leishmaniasis from non-endemic region [PDF]

, 2010
A case of atypical and acute presentation of visceral leishmaniasis from non-endemic region, characterised by exudative pleural effusion and hepatitis is ...
Gupta, D, Kashyap, R, Kaul, R, Raina, S
core   +1 more source

Attenuated Leishmania induce pro-inflammatory mediators and influence leishmanicidal activity by p38 MAPK dependent phagosome maturation in Leishmania donovani co-infected macrophages [PDF]

, 2016
Promastigote form of Leishmania, an intracellular pathogen, delays phagosome maturation and resides inside macrophages. But till date limited study has been done to manipulate the phagosomal machinery of macrophages to restrict Leishmania growth ...
A Awasthi, A Sarkar, AF Vinet, AF Vinet, AK Marr, BG Bolscher, C Bucci, C Prive, D Aivazian, D Raoult, DJ Hackam, DorcasS Yole, E Aktas, E Cillari, E del Cerro-Vadillo, E van den Bogaart, EL Eskelinen, F Real, GF Spath, GJ Feng, HW Murray, J Rink, J van Griensven, JM Blander, JY Jung, KR Gantt, KW Beyenbach, L Kedzierski, L Kedzierski, M Bhattacharya, M Desjardins, M Desjardins, M Junghae, M Olivier, ME Winberg, ML Schmitz, MS Gomes, N Courret, N Moradin, NC Peters, OV Vieira, PS Veras, RA Heinzen, RK Mathur, S Bhardwaj, S Duclos, S Ghosh, S Mukhopadhyay, S Mukhopadhyay, S Noazin, S Scianimanico, SD Reid, T Lang, V Cavalli, WK Andreoli, Y Osorio, Z Sun   +56 more
core   +1 more source