Results 121 to 130 of about 26,266 (223)
The role of CD4+ T cells in visceral leishmaniasis; new and emerging roles for NKG7 and TGFβ
Frontiers in Cellular and Infection MicrobiologyVisceral leishmaniasis is a potentially devastating neglected tropical disease caused by the protozoan parasites Leishmania donovani and L. infantum (chagasi).
Jinrui Na, Jinrui Na, Christian Engwerda
doaj +1 more source
Vaccination with Leishmania infantum Acidic Ribosomal P0 but Not with Nucleosomal Histones Proteins Controls Leishmania infantum Infection in Hamsters [PDF]
, 2015 Several intracellular Leishmania antigens have been identified in order to find a potential vaccine capable of conferring long lasting protection against Leishmania infection.
Abbehusen, M. +11 more
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Cutaneous Leishmaniasis Vaccination: A Matter of Quality
Frontiers in Immunology, 2016 There have been exhaustive efforts to develop an efficient vaccine against Leishmaniasis. Factors like host and parasite genetic characteristics, virulence, epidemiological scenarios and, mainly, diverse immune responses triggered by Leishmania species ...
Paula Mello De Luca +1 more
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International Journal of Infectious DiseasesObjectives: In immunocompromised patients, asymptomatic Leishmania infection can reactivate, and evolve to severe disease. To date, no test is considered the gold standard for the identification of asymptomatic Leishmania infection.
Alessandro Deni +14 more
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Analysis of the role of the p47 GTPase IIGP1 in Resistance against Intracellular Pathogens [PDF]
, 2005 IIGP1 is a member of the p47 GTPase family of IFNγ-induced proteins, which are among the most potent presently known mediators of cell-autonomous resistance against intracellular bacterial and protozoan pathogens in the mouse. From all studied members of
Parvanova, Iana Angelova
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Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis [PDF]
, 2012 There are currently no effective vaccines for visceral leishmaniasis, the second most deadly parasitic infection in the world. Here, we describe a novel whole-cell vaccine approach using Leishmania infantum chagasi promastigotes treated with the psoralen
Beverley, Stephen M +11 more
core +2 more sources
Memorias do Instituto Oswaldo Cruz, 2010 This study evaluated two vaccine candidates for their effectiveness in protecting BALB/c mice against Leishmania chagasiinfection. These immunogenic preparations were composed of Leishmania amazonensisor Leishmania braziliensisantigenic extracts in ...
Rafaella FQ Grenfell +6 more
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, 2021 Leishmania cysteine proteases are important virulence factors involved in host-parasite interaction. Previous studies revealed an important role for cysteine proteases in modulation of the T helper cell responses through interfering with macrophage functions or by targeting certain immune modulators for degradation.
openaire +2 more sources
Asymptomatic immune responders to Leishmania among HIV positive patients.
PLoS Neglected Tropical Diseases, 2019 Concomitant infection with human immunodeficiency virus (HIV) and the Leishmania parasite is a growing public health problem, the result of the former spreading to areas where the latter is endemic.
Laura Botana +8 more
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Increased Levels of IL-10, IL-12, and IFN-gamma in Patients with Visceral Leishmaniasis [PDF]
, 2009 Visceral leishmaniasis remains a serious public health problem in developing countries. Cytokines have a crucial role in the pathogenesis of this disease.
Abdolvahab, Alborz. +5 more
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